第一手 SEC EDGAR 13F-HR 機構持倉:依市值排序的前 25 大持有人，以及本季增持 / 減持最多的機構。季度 2026-03-31。
| 申報機構 | 持股數 | 市值 | Δ 持股 | 變動 |
|---|---|---|---|---|
ORBIMED ADVISORS LLCCIK 0001055951 | 1,027,944 | $7.00M | – | no_change |
FRANKLIN RESOURCES INCCIK 0000038777 | 626,571 | $4.27M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 381,823 | $2.60M | +274,009 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 336,524 | $2.29M | +336,524 | NEW |
Woodline Partners LPCIK 0001784547 | 313,124 | $2.13M | -311,876 | ↓ DEC |
Prosight Management, LPCIK 0001617201 | 250,244 | $1.70M | – | no_change |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 232,591 | $1.58M | -10,354 | ↓ DEC |
Stonepine Capital Management, LLCCIK 0001440771 | 221,955 | $1.51M | +1,944 | ↑ INC |
Alyeska Investment Group, L.P.CIK 0001453072 | 203,799 | $1.39M | – | no_change |
Carlyle Group Inc.CIK 0001527166 | 184,295 | $1.26M | – | no_change |
NEXTBio Capital Management LPCIK 0002038158 | 157,827 | $1.07M | – | no_change |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 101,135 | $689.04K | +12,279 | ↑ INC |
DAFNA Capital Management LLCCIK 0001389933 | 93,812 | $638.86K | – | no_change |
Burkehill Global Management, LPCIK 0001904549 | 62,500 | $425.63K | – | no_change |
Rangeley Capital, LLCCIK 0001517796 | 56,000 | $381.36K | +30,999 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 53,827 | $366.56K | -74,819 | ↓ DEC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 52,900 | $360.25K | +52,900 | NEW |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 50,334 | $342.77K | +50,334 | NEW |
Trexquant Investment LPCIK 0001633445 | 43,666 | $297.37K | +43,666 | NEW |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 43,106 | $293.55K | -101,690 | ↓ DEC |
RBF Capital, LLCCIK 0001134621 | 38,582 | $262.74K | – | no_change |
UBS Group AGCIK 0001610520 | 38,368 | $261.29K | +34,571 | ↑ INC |
JANE STREET GROUP, LLCCIK 0001595888 | 37,084 | $252.54K | +37,084 | NEW |
BlackRock, Inc.CIK 0002012383 | 36,585 | $249.14K | – | no_change |
STATE STREET CORPCIK 0000093751 | 36,222 | $246.67K | +10,326 | ↑ INC |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +336,524 | $2.29M |
CITADEL ADVISORS LLC↑ INC | +274,009 | $2.60M |
SUSQUEHANNA INTERNATIONAL GROUP, LLPNEW | +52,900 | $360.25K |
VANGUARD FIDUCIARY TRUST CONEW | +50,334 | $342.77K |
Trexquant Investment LPNEW | +43,666 | $297.37K |
JANE STREET GROUP, LLCNEW | +37,084 | $252.54K |
UBS Group AG↑ INC | +34,571 | $261.29K |
Rangeley Capital, LLC↑ INC | +30,999 | $381.36K |
OCCUDO QUANTITATIVE STRATEGIES LPNEW | +15,100 | $114.00K |
Vontobel Holding Ltd.NEW | +14,247 | $97.02K |
| 申報機構 | Δ 持股 | 市值 |
|---|---|---|
Woodline Partners LP↓ DEC | -311,876 | $2.13M |
TWO SIGMA INVESTMENTS, LP↓ DEC | -101,690 | $293.55K |
ADAR1 Capital Management, LLC↓ DEC | -74,819 | $366.56K |
ACADIAN ASSET MANAGEMENT LLC↓ DEC | -63,257 | $802.00 |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -10,354 | $1.58M |
ROYAL BANK OF CANADA↓ DEC | -3,750 | $11.00K |
FNY Investment Advisers, LLC↓ DEC | -2,900 | $21.00 |
JPMORGAN CHASE & CO↓ DEC | -4 | $49.00 |