First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Bain Capital Life Sciences Investors, LLCCIK 0001703031 | 664,021 | $5.58M | +664,021 | NEW |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 422,505 | $3.55M | +422,505 | NEW |
Sio Capital Management, LLCCIK 0001482416 | 152,464 | $1.28M | +152,464 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 123,660 | $1.04M | +123,660 | NEW |
Caligan Partners LPCIK 0001727492 | 112,128 | $943.00K | +112,128 | NEW |
Merck & Co., Inc.CIK 0000310158 | 105,982 | $891.31K | +105,982 | NEW |
Stonepine Capital Management, LLCCIK 0001440771 | 64,162 | $539.60K | +64,162 | NEW |
MORGAN STANLEYCIK 0000895421 | 57,493 | $483.52K | +57,493 | NEW |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 49,566 | $416.85K | +49,566 | NEW |
AJU IB Investment Co., Ltd.CIK 0001710065 | 47,695 | $401.12K | +47,695 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 37,197 | $312.85K | +37,197 | NEW |
FMR LLCCIK 0000315066 | 36,558 | $307.45K | +36,558 | NEW |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 28,475 | $239.47K | +28,475 | NEW |
Velan Capital Investment Management LPCIK 0001848809 | 14,285 | $120.14K | +14,285 | NEW |
Ghisallo Capital Management LLCCIK 0001825214 | 13,800 | $116.06K | +13,800 | NEW |
STATE STREET CORPCIK 0000093751 | 13,311 | $111.95K | +13,311 | NEW |
CWM, LLCCIK 0001535847 | 4,206 | $35.37K | +4,206 | NEW |
UBS Group AGCIK 0001610520 | 4,038 | $33.96K | +4,038 | NEW |
JPMORGAN CHASE & COCIK 0000019617 | 240 | $1.98K | +240 | NEW |
Vanguard Global Advisers, LLCCIK 0001811242 | 210 | $1.77K | +210 | NEW |
ROYAL BANK OF CANADACIK 0001000275 | 91 | $1.00K | +91 | NEW |
Key FInancial IncCIK 0001801720 | 59 | $496.00 | +59 | NEW |
GSA CAPITAL PARTNERS LLPCIK 0001362033 | 16,946 | $143.00 | +16,946 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
Bain Capital Life Sciences Investors, LLCNEW | +664,021 | $5.58M |
Frazier Life Sciences Management, L.P.NEW | +422,505 | $3.55M |
Sio Capital Management, LLCNEW | +152,464 | $1.28M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +123,660 | $1.04M |
Caligan Partners LPNEW | +112,128 | $943.00K |
Merck & Co., Inc.NEW | +105,982 | $891.31K |
Stonepine Capital Management, LLCNEW | +64,162 | $539.60K |
MORGAN STANLEYNEW | +57,493 | $483.52K |
RENAISSANCE TECHNOLOGIES LLCNEW | +49,566 | $416.85K |
AJU IB Investment Co., Ltd.NEW | +47,695 | $401.12K |