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Institutional Holders · 13F

First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.

Ownership

Institutions96.9%
Insiders0.8%
Institutions Count284
Institutions 96.9%Insiders 0.8%Float (Other) 2.4%
13F Filers (top 25)25Quarter 2026-03-31
Top-25 Reported Value$3.63BSum of shown holders' market value
Net Position Change10 adds · 10 trimsLargest movers this quarter

Top Holders by Value

25 shown
FilerSharesMarket ValueΔ SharesChange
FMR LLCCIK 0000315066
10,818,491$629.10M+1,898,241↑ INC
Avoro Capital Advisors LLCCIK 0001633313
5,777,777$335.98M+353,333↑ INC
BlackRock, Inc.CIK 0002012383
5,640,118$327.97M+539,834↑ INC
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219
4,829,641$280.84M+64,862↑ INC
DRIEHAUS CAPITAL MANAGEMENT LLCCIK 0000938206
4,491,653$261.19M-47,038↓ DEC
CITADEL ADVISORS LLCCIK 0001423053
2,886,390$167.84M+1,456,677↑ INC
Capital International InvestorsCIK 0001562230
2,674,727$155.54M-740,232↓ DEC
JPMORGAN CHASE & COCIK 0000019617
1,923,610$106.86M+429,578↑ INC
STATE STREET CORPCIK 0000093751
1,720,533$100.05M+227,983↑ INC
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194
1,695,037$98.57M+1,557,918↑ INC
Affinity Asset Advisors, LLCCIK 0001773195
1,675,000$97.40M+425,000↑ INC
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258
1,615,696$93.95M+1,073,676↑ INC
Holocene Advisors, LPCIK 0001700574
1,518,686$88.31M+236,605↑ INC
WESTFIELD CAPITAL MANAGEMENT CO LPCIK 0001177719
1,401,483$81.50M+174,712↑ INC
Caligan Partners LPCIK 0001727492
1,393,027$81.00M+293,662↑ INC
BNP Paribas Asset Management Holding S.A.CIK 0001520354
1,342,028$78.04M+281,807↑ INC
BRAIDWELL LPCIK 0001920938
1,338,452$77.83M-486,624↓ DEC
Caption Management, LLCCIK 0001706766
1,337,900$77.80M+757,900↑ INC
JENNISON ASSOCIATES LLCCIK 0000053417
1,318,814$76.69M+26,759↑ INC
Siren, L.L.C.CIK 0002005245
1,318,564$76.67M+505,803↑ INC
Alyeska Investment Group, L.P.CIK 0001453072
1,299,469$75.56M+932,236↑ INC
FRANKLIN RESOURCES INCCIK 0000038777
1,280,577$74.47M+522,518↑ INC
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717
1,092,932$63.55M+140,253↑ INC
ALLIANCEBERNSTEIN L.P.CIK 0001109448
1,403,297$62.90M-190,517↓ DEC
ORBIMED ADVISORS LLCCIK 0001055951
1,059,971$61.64M+612,771↑ INC

Top Adds (Buyers)

FilerΔ SharesValue
FMR LLC↑ INC
+1,898,241$629.10M
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC
+1,557,918$98.57M
CITADEL ADVISORS LLC↑ INC
+1,456,677$167.84M
DEERFIELD MANAGEMENT COMPANY, L.P.↑ INC
+1,073,676$93.95M
Alyeska Investment Group, L.P.↑ INC
+932,236$75.56M
T. Rowe Price Investment Management, Inc.↑ INC
+859,408$55.36K
Caption Management, LLC↑ INC
+757,900$77.80M
ORBIMED ADVISORS LLC↑ INC
+612,771$61.64M
VANGUARD PORTFOLIO MANAGEMENT LLCNEW
+543,062$31.58M
BlackRock, Inc.↑ INC
+539,834$327.97M

Top Trims (Sellers)

FilerΔ SharesValue
Commodore Capital LP↓ DEC
-975,000$47.97M
Capital International Investors↓ DEC
-740,232$155.54M
BRAIDWELL LP↓ DEC
-486,624$77.83M
MILLENNIUM MANAGEMENT LLC↓ DEC
-433,271$11.73M
BARCLAYS PLC↓ DEC
-362,755$13.85M
STEMPOINT CAPITAL LP↓ DEC
-207,850$8.18M
ALLIANCEBERNSTEIN L.P.↓ DEC
-190,517$62.90M
TimesSquare Capital Management, LLC↓ DEC
-173,447$20.89M
Aberdeen Group plc↓ DEC
-140,362$35.47M
Rhenman & Partners Asset Management AB↓ DEC
-111,000$1.63M