First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
TRV GP V, LLCCIK 0001990717 | 6,215,591 | $149.36M | – | no_change |
DRIEHAUS CAPITAL MANAGEMENT LLCCIK 0000938206 | 4,395,572 | $105.63M | -413,898 | ↓ DEC |
TRV GP VI, LLCCIK 0001990716 | 4,211,659 | $101.21M | – | no_change |
Samsara BioCapital, LLCCIK 0001744967 | 3,149,128 | $75.67M | – | no_change |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 2,906,427 | $69.84M | +191,298 | ↑ INC |
Siren, L.L.C.CIK 0002005245 | 2,000,000 | $48.06M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 1,822,174 | $43.79M | +20,846 | ↑ INC |
BVF INC/ILCIK 0001056807 | 1,353,249 | $32.52M | -367,533 | ↓ DEC |
Avoro Capital Advisors LLCCIK 0001633313 | 1,337,500 | $32.14M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,196,962 | $28.76M | +1,196,962 | NEW |
ADAR1 Capital Management, LLCCIK 0001940272 | 1,089,818 | $26.19M | -67,793 | ↓ DEC |
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212 | 1,048,834 | $25.20M | +502,734 | ↑ INC |
First Light Asset Management, LLCCIK 0001600004 | 732,860 | $17.61M | +112,049 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 645,146 | $15.51M | +72,412 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 631,447 | $15.17M | +91,419 | ↑ INC |
Casdin Capital, LLCCIK 0001534261 | 553,268 | $13.30M | – | no_change |
Venrock Adviser, LLCCIK 0001615982 | 506,056 | $12.16M | -104,752 | ↓ DEC |
Catalio Capital Management, LPCIK 0001958125 | 294,360 | $7.07M | – | no_change |
Soleus Capital Management, L.P.CIK 0001802630 | 275,000 | $6.61M | -108,368 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 236,679 | $5.69M | +233,108 | ↑ INC |
Universal- Beteiligungs- und Servicegesellschaft mbHCIK 0002057170 | 223,995 | $5.38M | +1,293 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 195,043 | $4.69M | +195,043 | NEW |
Kalehua Capital Management LLCCIK 0002106181 | 194,544 | $4.67M | – | no_change |
CHARLES SCHWAB INVESTMENT MANAGEMENT INCCIK 0000884546 | 181,580 | $4.36M | -5,661 | ↓ DEC |
NORTHERN TRUST CORPCIK 0000073124 | 164,530 | $3.95M | +10,334 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,196,962 | $28.76M |
PRIMECAP MANAGEMENT CO/CA/↑ INC | +502,734 | $25.20M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +233,108 | $5.69M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +195,043 | $4.69M |
GOLDMAN SACHS GROUP INC↑ INC | +191,298 | $69.84M |
VANGUARD FIDUCIARY TRUST CONEW | +154,484 | $3.71M |
First Light Asset Management, LLC↑ INC | +112,049 | $17.61M |
HUSSMAN STRATEGIC ADVISORS, INC.NEW | +105,000 | $2.52M |
STATE STREET CORP↑ INC | +91,419 | $15.17M |
GEODE CAPITAL MANAGEMENT, LLC↑ INC | +72,412 | $15.51M |
| Filer | Δ Shares | Value |
|---|---|---|
DRIEHAUS CAPITAL MANAGEMENT LLC↓ DEC | -413,898 | $105.63M |
BVF INC/IL↓ DEC | -367,533 | $32.52M |
MARSHALL WACE, LLP↓ DEC | -187,061 | $957.35K |
Checkpoint Capital L.P.↓ DEC | -182,858 | $2.41M |
Soleus Capital Management, L.P.↓ DEC | -108,368 | $6.61M |
Venrock Adviser, LLC↓ DEC | -104,752 | $12.16M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↓ DEC | -95,600 | $1.75M |
Invesco Ltd.↓ DEC | -79,146 | $1.99M |
ADAR1 Capital Management, LLC↓ DEC | -67,793 | $26.19M |
JACOBS LEVY EQUITY MANAGEMENT, INC↓ DEC | -32,934 | $683.32K |