| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 20, 2026 | Alex Slanix Paul | Director | A | 11,000 | $0.0000 | $0.00 |
| May 20, 2026 | Alex Slanix Paul | Director | A | 5,500 | $0.0000 | $0.00 |
| May 20, 2026 | Kaplan Johanne | Chief Development Officer | A | 50,000 | $0.0000 | $0.00 |
| May 20, 2026 | Mandel-Brehm Josh | Director | A | 11,000 | $0.0000 | $0.00 |
| May 20, 2026 | Mandel-Brehm Josh | Director | A | 5,500 | $0.0000 | $0.00 |
| May 20, 2026 | Milbury Max A. | Principal Accounting Officer | A | 18,167 | $0.0000 | $0.00 |
| May 20, 2026 | Cashman Neil | Chief Scientific Officer | A | 50,000 | $0.0000 | $0.00 |
| May 20, 2026 | Shafmaster Madge K. | Director | A | 11,000 | $0.0000 | $0.00 |
| May 20, 2026 | Shafmaster Madge K. | Director | A | 5,500 | $0.0000 | $0.00 |
| May 20, 2026 | Warma Neil K | Chief Executive Officer | A | 160,000 | $0.0000 | $0.00 |
| May 20, 2026 | Williams Eugene | Director | A | 11,000 | $0.0000 | $0.00 |
| May 20, 2026 | Williams Eugene | Director | A | 5,500 | $0.0000 | $0.00 |
| May 20, 2026 | WYMAN WILLIAM W | Director | A | 11,000 | $0.0000 | $0.00 |
| May 20, 2026 | WYMAN WILLIAM W | Director | A | 5,500 | $0.0000 | $0.00 |
| Apr 22, 2026 | Kirwin Patrick D. | Director | P | 4,000 | $11.3300 | $45.32K |
| Mar 5, 2026 | Williams Eugene | Director | P | 2,000 | $24.4000 | $48.80K |
| Mar 4, 2026 | Williams Eugene | Director | P | 2,000 | $24.0000 | $48.00K |
| Mar 3, 2026 | Williams Eugene | Director | P | 1,000 | $21.8900 | $21.89K |
| Mar 2, 2026 | Williams Eugene | Director | P | 1,000 | $22.5300 | $22.53K |
| Feb 19, 2026 | Kaplan Johanne | Chief Development Officer | P | 1,629 | $15.3500 | $25.00K |
| Feb 3, 2026 | ABG Management Ltd. | 10% Owner | P | 700,741 | – | – |
| Feb 3, 2026 | ABG Management Ltd. | 10% Owner | P | 700,741 | $12.1300 | $8.50M |
| Feb 3, 2026 | Kirwin Patrick D. | Director | A | 3,050 | – | – |
| Feb 3, 2026 | Kirwin Patrick D. | Director | A | 3,050 | $12.1300 | $37.00K |
| Feb 3, 2026 | Milbury Max A. | Other | A | 6,595 | – | – |
| Feb 3, 2026 | Milbury Max A. | Other | A | 6,595 | $12.1300 | $80.00K |
| Feb 3, 2026 | Warma Neil K | Chief Executive Officer | A | 6,183 | – | – |
| Feb 3, 2026 | Warma Neil K | Chief Executive Officer | A | 6,183 | $12.1300 | $75.00K |
| Feb 3, 2026 | Cashman Neil | Chief Scientific Officer | A | 4,122 | – | – |
| Feb 3, 2026 | Cashman Neil | Chief Scientific Officer | A | 4,122 | $12.1300 | $50.00K |
| Feb 3, 2026 | Kaplan Johanne | Chief Development Officer | A | 2,060 | – | – |
| Feb 3, 2026 | Kaplan Johanne | Chief Development Officer | A | 2,060 | $12.1300 | $24.99K |
| Oct 22, 2025 | ABG Management Ltd. | 10% Owner | A | 40,000 | $0.0000 | $0.00 |
| Oct 3, 2025 | Milbury Max A. | Other | P | 30,392 | $0.4912 | $14.93K |
| Sep 22, 2025 | Kaplan Johanne | Chief Development Officer | A | 165,000 | $0.0000 | $0.00 |
| Sep 22, 2025 | ALTSTIEL LARRY DOUGLAS | Chief Medical Officer | A | 165,000 | $0.0000 | $0.00 |
| Sep 22, 2025 | Milbury Max A. | Other | A | 60,000 | $0.0000 | $0.00 |
| Sep 22, 2025 | Warma Neil K | Chief Executive Officer | A | 600,000 | $0.0000 | $0.00 |
| Sep 22, 2025 | Cashman Neil | Chief Scientific Officer | A | 165,000 | $0.0000 | $0.00 |
| Jul 29, 2025 | Sclar Jeremy M. | 10% Owner | P | 3,139,533 | – | – |
| Jul 29, 2025 | Jeremy M. Sclar 2012 Irrevocable Family Trust | 10% Owner | P | 3,139,533 | – | – |
| Jul 29, 2025 | GORDON MICHAEL S | 10% Owner | P | 539,100 | – | – |
| Jul 29, 2025 | Title 19 Promis | 10% Owner | P | 539,100 | – | – |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | $0.0000 | $0.00 |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | $0.0000 | $0.00 |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | $0.0000 | $0.00 |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | – | – |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | – | – |
| Jul 25, 2025 | Sclar Jeremy M. | 10% Owner | X | 697,674 | – | – |
| Jul 25, 2025 | Jeremy M. Sclar 2012 Irrevocable Family Trust | 10% Owner | X | 697,674 | $0.0000 | $0.00 |