| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 18, 2026 | KEATING LAURIE | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | HENSON HEIDI | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Dable Habib J | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Finer Mitchell H. | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Mayer Howard | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Resnick Joshua | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | Wyman Lisa | Director | A | 34,000 | $0.0000 | $0.00 |
| Jun 18, 2026 | RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | A | 34,000 | $0.0000 | $0.00 |
| May 21, 2026 | Kasraian Kasra | Chief Technical Officer | S | 1,233 | $1.4107 | $1.74K |
| Mar 4, 2026 | McArthur James G | President and CEO | S | 131 | $6.3250 | $828.00 |
| Mar 4, 2026 | McArthur James G | President and CEO | S | 5,144 | $6.2300 | $32.05K |
| Mar 4, 2026 | Donnelly Noel | Chief Financial Officer | S | 52 | $6.3250 | $328.00 |
| Mar 4, 2026 | Donnelly Noel | Chief Financial Officer | S | 2,032 | $6.2300 | $12.66K |
| Mar 4, 2026 | STRECK PAUL | EVP, Head of R&D | S | 47 | $6.2880 | $295.00 |
| Mar 4, 2026 | STRECK PAUL | EVP, Head of R&D | S | 1,832 | $6.2300 | $11.41K |
| Mar 1, 2026 | McArthur James G | President and CEO | A | 731,250 | $0.0000 | $0.00 |
| Mar 1, 2026 | McArthur James G | President and CEO | A | 187,688 | $0.0000 | $0.00 |
| Mar 1, 2026 | Donnelly Noel | Chief Financial Officer | A | 300,000 | $0.0000 | $0.00 |
| Mar 1, 2026 | Donnelly Noel | Chief Financial Officer | A | 76,793 | $0.0000 | $0.00 |
| Mar 1, 2026 | STRECK PAUL | EVP, Head of R&D | A | 196,500 | $0.0000 | $0.00 |
| Mar 1, 2026 | STRECK PAUL | EVP, Head of R&D | A | 50,300 | $0.0000 | $0.00 |
| Mar 1, 2026 | Kasraian Kasra | Chief Technical Officer | A | 135,000 | $0.0000 | $0.00 |
| Mar 1, 2026 | Kasraian Kasra | Chief Technical Officer | A | 34,557 | $0.0000 | $0.00 |
| Mar 1, 2026 | Vittiglio Joseph | Chief Business & Legal Officer | A | 120,000 | $0.0000 | $0.00 |
| Mar 1, 2026 | Vittiglio Joseph | Chief Business & Legal Officer | A | 30,717 | $0.0000 | $0.00 |
| Dec 8, 2025 | Vittiglio Joseph | Chief Business & Legal Officer | A | 160,000 | $0.0000 | $0.00 |
| Dec 8, 2025 | Vittiglio Joseph | Chief Business & Legal Officer | A | 35,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | A | 144,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | D | 144,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | A | 144,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | D | 144,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | A | 169,037 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | D | 169,037 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | A | 203,339 | $0.0000 | $0.00 |
| Nov 4, 2025 | Donnelly Noel | Chief Financial Officer | D | 203,339 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 300,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 300,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 275,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 275,000 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 466,095 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 466,095 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 40,815 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | A | 352,705 | $0.0000 | $0.00 |
| Nov 4, 2025 | McArthur James G | President and CEO | D | 352,705 | $0.0000 | $0.00 |
| Nov 4, 2025 | STRECK PAUL | EVP, Head of R&D | A | 40,000 | $0.0000 | $0.00 |