| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 25, 2026 | Lynx1 Capital Management LP | 10% Owner | P | 50,055 | $4.1175 | $206.10K |
| May 19, 2026 | Countouriotis Athena | Director | A | 10,539 | $0.0000 | $0.00 |
| May 19, 2026 | GOWEN MAXINE | Director | A | 10,539 | $0.0000 | $0.00 |
| May 19, 2026 | Kapadia Sandip | Director | A | 10,539 | $0.0000 | $0.00 |
| May 19, 2026 | Kassberg Thomas Richard | Director | A | 10,539 | $0.0000 | $0.00 |
| May 19, 2026 | Porter Derrell | Director | A | 10,539 | $0.0000 | $0.00 |
| May 19, 2026 | Sondhi Dolan | Director | A | 10,539 | $0.0000 | $0.00 |
| Mar 16, 2026 | Chou William | PRESIDENT AND CEO | A | 58,000 | $0.0000 | $0.00 |
| Mar 16, 2026 | Borthwick Kathleen | CFO | A | 15,610 | $0.0000 | $0.00 |
| Jan 8, 2026 | Borthwick Kathleen | CFO | M | 5,000 | $0.0000 | $0.00 |
| Jan 8, 2026 | Borthwick Kathleen | CFO | S | 2,062 | $18.4394 | $38.02K |
| Jan 8, 2026 | Borthwick Kathleen | CFO | M | 5,000 | – | – |
| Jan 8, 2026 | Chou William | PRESIDENT AND CEO | M | 10,000 | $0.0000 | $0.00 |
| Jan 8, 2026 | Chou William | PRESIDENT AND CEO | S | 4,076 | $18.4394 | $75.16K |
| Jan 8, 2026 | Chou William | PRESIDENT AND CEO | M | 10,000 | – | – |
| Sep 15, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 11,900 | $6.9895 | $83.17K |
| Sep 12, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 19,783 | $6.9908 | $138.30K |
| Sep 11, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 325 | $6.9558 | $2.26K |
| Jul 24, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 66,423 | $5.7127 | $379.45K |
| Jul 23, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 49,302 | $5.7408 | $283.03K |
| Jul 22, 2025 | Lynx1 Capital Management LP | 10% Owner | P | 13,123 | $5.4361 | $71.34K |
| Jun 26, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 213,257 | $0.3300 | $70.37K |
| Jun 25, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 138,800 | $0.3300 | $45.80K |
| Jun 24, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 231,600 | $0.3500 | $81.06K |
| May 28, 2025 | Kassberg Thomas Richard | Director | A | 143,789 | $0.0000 | $0.00 |
| May 28, 2025 | Porter Derrell | Director | A | 201,857 | $0.0000 | $0.00 |
| May 28, 2025 | Islam Saqib | Director | A | 201,857 | $0.0000 | $0.00 |
| May 28, 2025 | Countouriotis Athena | Director | A | 201,857 | $0.0000 | $0.00 |
| May 28, 2025 | Sondhi Dolan | Director | A | 201,857 | $0.0000 | $0.00 |
| May 28, 2025 | GOWEN MAXINE | Director | A | 201,857 | $0.0000 | $0.00 |
| May 28, 2025 | Kapadia Sandip | Director | A | 201,857 | $0.0000 | $0.00 |
| Apr 24, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 68,195 | $0.3200 | $21.82K |
| Apr 23, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 89,328 | $0.3400 | $30.37K |
| Apr 22, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 78,049 | $0.3400 | $26.54K |
| Apr 17, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 77,090 | $0.3300 | $25.44K |
| Apr 16, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 61,638 | $0.3300 | $20.34K |
| Apr 15, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 10,326 | $0.3800 | $3.92K |
| Mar 15, 2025 | Cale Edgar B. | GC & CORPORATE SECRETARY | A | 278,386 | $0.0000 | $0.00 |
| Mar 15, 2025 | Chou William | PRESIDENT AND CEO | A | 779,533 | $0.0000 | $0.00 |
| Mar 15, 2025 | Borthwick Kathleen | CFO | A | 278,386 | $0.0000 | $0.00 |
| Feb 11, 2025 | Borthwick Kathleen | CFO | S | 3,183 | $0.5296 | $1.69K |
| Feb 10, 2025 | Borthwick Kathleen | CFO | M | 8,000 | $0.0000 | $0.00 |
| Feb 10, 2025 | Borthwick Kathleen | CFO | M | 8,000 | – | – |
| Jan 15, 2025 | Chou William | PRESIDENT AND CEO | A | 20,000 | $0.0000 | $0.00 |
| Jan 15, 2025 | Borthwick Kathleen | CFO | A | 10,000 | $0.0000 | $0.00 |
| Jan 14, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 79,024 | $0.6000 | $47.41K |
| Jan 13, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 17,986 | $0.6400 | $11.51K |
| Jan 10, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 126,209 | $0.6600 | $83.30K |
| Jan 8, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 75,007 | $0.6800 | $51.00K |
| Jan 7, 2025 | ORBIMED ADVISORS LLC | 10% Owner | S | 52,536 | $0.7100 | $37.30K |