| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 22, 2026 | Leverone Jason A. | Chief Financial Officer | S | 303 | $4.3963 | $1.33K |
| Jun 22, 2026 | Saccomano Nicholas A | President and CEO | S | 86 | $4.3963 | $378.00 |
| Jun 4, 2026 | Carruthers R Michael | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Jansen Valerie Malyvanh | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | GREY MICHAEL G | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Phillips Andrew John | Director | A | 7,650 | $0.0000 | $0.00 |
| Jun 4, 2026 | Ratcliffe Liam | Director | A | 1,275 | $0.0000 | $0.00 |
| Jun 4, 2026 | Mathers Edward T | Director | A | 7,650 | $0.0000 | $0.00 |
| Apr 1, 2026 | Hartley Dylan | Chief Scientific Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Leverone Jason A. | Chief Financial Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Agresta Samuel | Chief Medical Officer | A | 110,000 | $0.0000 | $0.00 |
| Apr 1, 2026 | Saccomano Nicholas A | President and CEO | A | 330,000 | $0.0000 | $0.00 |
| Mar 31, 2026 | Ratcliffe Liam | Director | A | 15,300 | $0.0000 | $0.00 |
| Mar 23, 2026 | Leverone Jason A. | Chief Financial Officer | S | 301 | $4.1565 | $1.25K |
| Mar 23, 2026 | Saccomano Nicholas A | President and CEO | S | 86 | $4.1565 | $357.00 |
| Dec 31, 2025 | Manke Isaac | Director | A | 5,258 | $0.0000 | $0.00 |
| Dec 31, 2025 | Mathers Edward T | Director | A | 3,911 | $0.0000 | $0.00 |
| Dec 22, 2025 | Leverone Jason A. | Chief Financial Officer | S | 302 | $2.9677 | $896.00 |
| Dec 22, 2025 | Saccomano Nicholas A | President and CEO | S | 87 | $2.9677 | $258.00 |
| Sep 30, 2025 | Manke Isaac | Director | A | 5,545 | $0.0000 | $0.00 |
| Sep 30, 2025 | Mathers Edward T | Director | A | 4,125 | $0.0000 | $0.00 |
| Sep 22, 2025 | Leverone Jason A. | Chief Financial Officer | S | 303 | $2.6235 | $794.00 |
| Sep 22, 2025 | Saccomano Nicholas A | President and CEO | S | 88 | $2.6235 | $230.00 |
| Jun 30, 2025 | Manke Isaac | Director | A | 6,311 | $0.0000 | $0.00 |
| Jun 30, 2025 | Mathers Edward T | Director | A | 4,694 | $0.0000 | $0.00 |
| Jun 23, 2025 | Leverone Jason A. | Chief Financial Officer | S | 303 | $2.3842 | $722.00 |
| Jun 23, 2025 | Saccomano Nicholas A | President and CEO | S | 88 | $2.3842 | $209.00 |
| May 28, 2025 | Carruthers R Michael | Director | A | 7,650 | $0.0000 | $0.00 |
| May 28, 2025 | GREY MICHAEL G | Director | A | 7,650 | $0.0000 | $0.00 |
| May 28, 2025 | Jansen Valerie Malyvanh | Director | A | 7,650 | $0.0000 | $0.00 |
| May 28, 2025 | Manke Isaac | Director | A | 7,650 | $0.0000 | $0.00 |
| May 28, 2025 | Phillips Andrew John | Director | A | 7,650 | $0.0000 | $0.00 |
| May 28, 2025 | Mathers Edward T | Director | A | 7,650 | $0.0000 | $0.00 |
| May 15, 2025 | ACORN BIOVENTURES, L.P. | 10% Owner | P | 1,129,730 | $1.8500 | $2.09M |
| May 15, 2025 | ACORN BIOVENTURES, L.P. | 10% Owner | P | 270,270 | $1.8500 | $500.00K |
| May 15, 2025 | Cormorant Asset Management, LP | Other | S | 1,813,439 | $1.8545 | $3.36M |
| May 12, 2025 | Cormorant Asset Management, LP | 10% Owner | S | 24,300 | $1.9850 | $48.23K |
| Apr 7, 2025 | Leverone Jason A. | Chief Financial Officer | S | 1,844 | $2.6710 | $4.92K |
| Apr 7, 2025 | Saccomano Nicholas A | President and CEO | S | 516 | $2.6710 | $1.38K |
| Apr 4, 2025 | Leverone Jason A. | Chief Financial Officer | S | 1,278 | $3.3276 | $4.25K |
| Apr 4, 2025 | Saccomano Nicholas A | President and CEO | S | 358 | $3.3276 | $1.19K |
| Mar 31, 2025 | Manke Isaac | Director | A | 3,469 | $0.0000 | $0.00 |
| Mar 31, 2025 | Mathers Edward T | Director | A | 2,580 | $0.0000 | $0.00 |
| Jan 27, 2025 | Agresta Samuel | Chief Medical Officer | A | 45,000 | $0.0000 | $0.00 |
| Jan 27, 2025 | Hartley Dylan | Chief Scientific Officer | A | 45,000 | $0.0000 | $0.00 |
| Jan 27, 2025 | Saccomano Nicholas A | President and CEO | A | 130,000 | $0.0000 | $0.00 |
| Jan 27, 2025 | Leverone Jason A. | Chief Financial Officer | A | 65,000 | $0.0000 | $0.00 |
| Oct 7, 2024 | Leonard Braden Michael | Other | J | 102,076 | – | – |
| Oct 7, 2024 | Leonard Braden Michael | Other | J | 345,739 | – | – |
| Oct 4, 2024 | Agresta Samuel | Chief Medical Officer | A | 131,396 | $0.0000 | $0.00 |