| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 18, 2026 | KABAKOFF DAVID S | Director | A | 3,510 | $0.0000 | $0.00 |
| Jun 18, 2026 | Houston John G | Director | A | 2,340 | $0.0000 | $0.00 |
| Jun 18, 2026 | Webster Stephen W | Director | A | 2,340 | $0.0000 | $0.00 |
| Jun 18, 2026 | Feigal Ellen | Director | A | 2,340 | $0.0000 | $0.00 |
| Jun 18, 2026 | Borgman Anne Elizabeth | Director | A | 2,340 | $0.0000 | $0.00 |
| Jun 18, 2026 | Jones Elaine V | Director | A | 2,340 | $0.0000 | $0.00 |
| Jan 30, 2026 | Cobourn Steven P. | Chief Financial Officer | A | 14,670 | $0.0000 | $0.00 |
| Jan 30, 2026 | Kundu Sourav | Sr VP, Dev. & Mfg. | A | 8,270 | $0.0000 | $0.00 |
| Jan 30, 2026 | Shaw Kevin G. | Sr VP, General Counsel | A | 8,270 | $0.0000 | $0.00 |
| Jan 30, 2026 | Mayer Timothy | Chief Operating Officer | A | 14,670 | $0.0000 | $0.00 |
| Jan 30, 2026 | Richman Michael | President & CEO | A | 38,190 | $0.0000 | $0.00 |
| Jan 30, 2026 | Guha Udayan | Chief Medical Officer | A | 14,670 | $0.0000 | $0.00 |
| Jun 20, 2025 | Feigal Ellen | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2025 | Webster Stephen W | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2025 | Borgman Anne Elizabeth | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2025 | Jones Elaine V | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2025 | KABAKOFF DAVID S | Director | A | 28,050 | $0.0000 | $0.00 |
| Jun 20, 2025 | Houston John G | Director | A | 18,700 | $0.0000 | $0.00 |
| Jan 31, 2025 | Richman Michael | President & CEO | A | 305,500 | $0.0000 | $0.00 |
| Jan 31, 2025 | Cobourn Steven P. | Chief Financial Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2025 | Kundu Sourav | Sr VP, Dev. & Mfg. | A | 66,125 | $0.0000 | $0.00 |
| Jan 31, 2025 | Shaw Kevin G. | Sr VP, General Counsel | A | 66,125 | $0.0000 | $0.00 |
| Jan 31, 2025 | Langermann Sol | Chief Scientific Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2025 | Mayer Timothy | Chief Operating Officer | A | 117,375 | $0.0000 | $0.00 |
| Jun 20, 2024 | Feigal Ellen | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2024 | Borgman Anne Elizabeth | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2024 | Houston John G | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2024 | Jones Elaine V | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2024 | Webster Stephen W | Director | A | 18,700 | $0.0000 | $0.00 |
| Jun 20, 2024 | KABAKOFF DAVID S | Director | A | 28,050 | $0.0000 | $0.00 |
| Mar 29, 2024 | Cobourn Steven P. | Chief Financial Officer | A | 93,900 | $0.0000 | $0.00 |
| Mar 29, 2024 | Kundu Sourav | Sr VP, Dev. & Mfg. | A | 52,900 | $0.0000 | $0.00 |
| Mar 29, 2024 | Langermann Sol | Chief Scientific Officer | A | 93,900 | $0.0000 | $0.00 |
| Mar 29, 2024 | Mayer Timothy | Chief Operating Officer | A | 93,900 | $0.0000 | $0.00 |
| Mar 29, 2024 | Myint Han | Chief Medical Officer | A | 93,900 | $0.0000 | $0.00 |
| Mar 29, 2024 | Richman Michael | President & CEO | A | 244,400 | $0.0000 | $0.00 |
| Mar 29, 2024 | Shaw Kevin G. | Sr VP, General Counsel | A | 93,900 | $0.0000 | $0.00 |
| Jan 31, 2024 | Cobourn Steven P. | Chief Financial Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2024 | Kundu Sourav | Sr VP, Dev. & Mfg. | A | 66,125 | $0.0000 | $0.00 |
| Jan 31, 2024 | Langermann Sol | Chief Scientific Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2024 | Mayer Timothy | Chief Operating Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2024 | Myint Han | Chief Medical Officer | A | 117,375 | $0.0000 | $0.00 |
| Jan 31, 2024 | Shaw Kevin G. | Sr VP, General Counsel | A | 66,125 | $0.0000 | $0.00 |
| Jan 31, 2024 | Richman Michael | President & CEO | A | 305,500 | $0.0000 | $0.00 |
| Jun 22, 2023 | Borgman Anne Elizabeth | Director | A | 14,250 | $0.0000 | $0.00 |
| Jun 22, 2023 | Webster Stephen W | Director | A | 14,250 | $0.0000 | $0.00 |
| Jun 22, 2023 | Jones Elaine V | Director | A | 14,250 | $0.0000 | $0.00 |
| Jun 22, 2023 | Feigal Ellen | Director | A | 14,250 | $0.0000 | $0.00 |
| Jun 22, 2023 | Houston John G | Director | A | 14,250 | $0.0000 | $0.00 |
| Jun 22, 2023 | Khuong Chau Quang | Director | A | 14,250 | $0.0000 | $0.00 |