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Institutional Holders · 13F

First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.

Ownership

Institutions83.1%
Insiders57.5%
Institutions Count205
Institutions 83.1%Insiders 57.5%Float (Other) 0.0%
13F Filers (top 25)25Quarter 2026-03-31
Top-25 Reported Value$1.47BSum of shown holders' market value
Net Position Change10 adds · 10 trimsLargest movers this quarter

Top Holders by Value

25 shown
FilerSharesMarket ValueΔ SharesChange
FMR LLCCIK 0000315066
4,303,188$309.61M+4,202,059↑ INC
BVF INC/ILCIK 0001056807
2,559,595$184.16M+1,000,000↑ INC
Two Seas Capital LPCIK 0001823138
1,959,178$140.96M+1,213,993↑ INC
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119
1,197,055$86.13M+1,197,055NEW
TWO SIGMA INVESTMENTS, LPCIK 0001179392
930,741$66.97M+457,727↑ INC
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194
903,190$64.98M-255,120↓ DEC
Prosight Management, LPCIK 0001617201
735,000$52.88M+180,367↑ INC
BlackRock, Inc.CIK 0002012383
692,650$49.84M+47,043↑ INC
CITADEL ADVISORS LLCCIK 0001423053
665,431$47.88M+176,054↑ INC
MORGAN STANLEYCIK 0000895421
659,387$47.44M+92,966↑ INC
ARMISTICE CAPITAL, LLCCIK 0001601086
578,000$41.59M-18,000↓ DEC
Invesco Ltd.CIK 0000914208
567,458$40.83M+99,299↑ INC
Sofinnova Investments, Inc.CIK 0001631134
509,546$36.66M+70,916↑ INC
Woodline Partners LPCIK 0001784547
415,335$29.88M+311,335↑ INC
MILLENNIUM MANAGEMENT LLCCIK 0001273087
404,277$29.09M-49,798↓ DEC
Bronte Capital Management Pty Ltd.CIK 0001471085
400,756$28.83M+400,756NEW
EMERALD ADVISERS, LLCCIK 0001015083
394,604$28.39M+10,262↑ INC
Qube Research & Technologies LtdCIK 0001729829
390,675$28.11M+66,760↑ INC
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717
346,795$24.96M+92,434↑ INC
UBS Group AGCIK 0001610520
320,172$23.04M+32,611↑ INC
GREAT POINT PARTNERS LLCCIK 0001281446
316,453$22.77M+105,721↑ INC
Vestal Point Capital, LPCIK 0001974915
285,000$20.51M+285,000NEW
22NW, LPCIK 0001694297
281,115$20.23M-50,000↓ DEC
PRIMECAP MANAGEMENT CO/CA/CIK 0000763212
279,150$20.08M-1,000↓ DEC
ORBIMED ADVISORS LLCCIK 0001055951
275,000$19.79M+275,000NEW

Top Adds (Buyers)

FilerΔ SharesValue
FMR LLC↑ INC
+4,202,059$309.61M
Two Seas Capital LP↑ INC
+1,213,993$140.96M
VANGUARD CAPITAL MANAGEMENT LLCNEW
+1,197,055$86.13M
BVF INC/IL↑ INC
+1,000,000$184.16M
TWO SIGMA INVESTMENTS, LP↑ INC
+457,727$66.97M
LORD, ABBETT & CO. LLCNEW
+405,080$29.15K
Bronte Capital Management Pty Ltd.NEW
+400,756$28.83M
Woodline Partners LP↑ INC
+311,335$29.88M
Vestal Point Capital, LPNEW
+285,000$20.51M
ORBIMED ADVISORS LLCNEW
+275,000$19.79M

Top Trims (Sellers)

FilerΔ SharesValue
FARALLON CAPITAL MANAGEMENT, L.L.C.↓ DEC
-787,000$287.80K
Point72 Asset Management, L.P.↓ DEC
-438,055$961.54K
SUSQUEHANNA INTERNATIONAL GROUP, LLP↓ DEC
-255,120$64.98M
BALYASNY ASSET MANAGEMENT L.P.↓ DEC
-246,170$2.58M
RENAISSANCE TECHNOLOGIES LLC↓ DEC
-131,100$3.01M
GROUP ONE TRADING LLC↓ DEC
-107,600$2.20M
HRT FINANCIAL LP↓ DEC
-102,776$5.08K
BNP PARIBAS FINANCIAL MARKETS↓ DEC
-88,759$8.74M
ACADIAN ASSET MANAGEMENT LLC↓ DEC
-70,252$141.00
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.↓ DEC
-65,786$8.80M