First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
FRANKLIN RESOURCES INCCIK 0000038777 | 938,666 | $5.31M | +938,666 | NEW |
Siren, L.L.C.CIK 0002005245 | 892,074 | $5.02M | +892,074 | NEW |
Vivo Capital, LLCCIK 0001674712 | 813,666 | $4.58M | +813,666 | NEW |
Point72 Asset Management, L.P.CIK 0001603466 | 690,778 | $3.89M | +690,778 | NEW |
Avidity Partners Management LPCIK 0001791827 | 387,769 | $3.08M | +387,769 | NEW |
Woodline Partners LPCIK 0001784547 | 500,432 | $2.82M | +500,432 | NEW |
SPHERA FUNDS MANAGEMENT LTD.CIK 0001496201 | 489,207 | $2.75M | +489,207 | NEW |
SUVRETTA CAPITAL MANAGEMENT, LLCCIK 0001569064 | 475,000 | $2.67M | +475,000 | NEW |
Soleus Capital Management, L.P.CIK 0001802630 | 414,359 | $2.33M | +414,359 | NEW |
Saturn V Capital Management LPCIK 0001964437 | 350,000 | $1.97M | +350,000 | NEW |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 298,433 | $1.68M | +298,433 | NEW |
683 Capital Management, LLCCIK 0001404574 | 230,833 | $1.30M | +230,833 | NEW |
Empery Asset Management, LPCIK 0001469336 | 230,100 | $1.30M | +230,100 | NEW |
ADAR1 Capital Management, LLCCIK 0001940272 | 222,555 | $1.25M | +222,555 | NEW |
Stonepine Capital Management, LLCCIK 0001440771 | 100,000 | $563.00K | +100,000 | NEW |
CITADEL ADVISORS LLCCIK 0001423053 | 42,492 | $239.23K | +42,492 | NEW |
MORGAN STANLEYCIK 0000895421 | 21,183 | $119.26K | +21,183 | NEW |
JANE STREET GROUP, LLCCIK 0001595888 | 19,608 | $110.40K | +19,608 | NEW |
ROYAL BANK OF CANADACIK 0001000275 | 16,245 | $91.00K | +16,245 | NEW |
Monashee Investment Management LLCCIK 0001627608 | 12,000 | $67.56K | +12,000 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 11,907 | $67.04K | +11,907 | NEW |
Propel Bio Management, LLCCIK 0001969764 | 10,145 | $57.12K | +10,145 | NEW |
AXQ CAPITAL, LPCIK 0001916908 | 10,096 | $56.84K | +10,096 | NEW |
China Universal Asset Management Co., Ltd.CIK 0001906594 | 6,400 | $36.03K | +6,400 | NEW |
NATIONAL BANK OF CANADA /FI/CIK 0000926171 | 2,115 | $11.78K | +2,115 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
FRANKLIN RESOURCES INCNEW | +938,666 | $5.31M |
Siren, L.L.C.NEW | +892,074 | $5.02M |
Vivo Capital, LLCNEW | +813,666 | $4.58M |
Point72 Asset Management, L.P.NEW | +690,778 | $3.89M |
Woodline Partners LPNEW | +500,432 | $2.82M |
SPHERA FUNDS MANAGEMENT LTD.NEW | +489,207 | $2.75M |
SUVRETTA CAPITAL MANAGEMENT, LLCNEW | +475,000 | $2.67M |
Soleus Capital Management, L.P.NEW | +414,359 | $2.33M |
Avidity Partners Management LPNEW | +387,769 | $3.08M |
Saturn V Capital Management LPNEW | +350,000 | $1.97M |