| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 1, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Director | A | 151,000 | $99.9999 | $15.10M |
| May 1, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Director | A | 149,000 | $99.9999 | $14.90M |
| Feb 6, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Director, 10% Owner | P | 19,338 | $36.5500 | $706.80K |
| Feb 6, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Director, 10% Owner | P | 11,183 | $35.9700 | $402.25K |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,236,631 | – | – |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,236,631 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | P | 882,353 | $17.0000 | $15.00M |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | P | 192,647 | $17.0000 | $3.27M |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | P | 882,353 | $17.0000 | $15.00M |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | P | 192,647 | $17.0000 | $3.27M |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,171,121 | – | – |
| Feb 5, 2026 | ENRIGHT PATRICK G | Director, 10% Owner | C | 1,236,631 | – | – |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | 10% Owner | C | 1,236,631 | – | – |
| Feb 5, 2026 | Waldman Reid Alexander | Chief Executive Officer | C | 1,437 | – | – |
| Feb 5, 2026 | Waldman Reid Alexander | Chief Executive Officer | C | 1,437 | – | – |
| Feb 5, 2026 | Durso Timothy August | Chief Technical Officer | C | 1,473 | – | – |
| Feb 5, 2026 | Durso Timothy August | Chief Technical Officer | C | 1,473 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 117,112 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 78,075 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 78,075 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 148,794 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 148,794 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 33,706 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 33,706 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | P | 58,823 | $17.0000 | $999.99K |
| Feb 5, 2026 | Coric Vlad | Director | P | 58,823 | $17.0000 | $999.99K |
| Feb 5, 2026 | Coric Vlad | Director | C | 117,112 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 78,075 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 78,075 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 148,794 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 148,794 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 33,706 | – | – |
| Feb 5, 2026 | Coric Vlad | Director | C | 33,706 | – | – |
| Feb 5, 2026 | Grant-Kels Jane M. | Director | C | 2,455 | – | – |
| Feb 5, 2026 | Grant-Kels Jane M. | Director | C | 2,455 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 520,758 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 906,862 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 480,269 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | P | 294,117 | $17.0000 | $5.00M |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 520,758 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 906,862 | – | – |
| Feb 5, 2026 | CHILDS JOHN W | Director | C | 480,269 | – | – |
| Feb 5, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Director, 10% Owner | P | 16,563 | $39.8000 | $659.21K |