First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
BAKER BROS. ADVISORS LPCIK 0001263508 | 19,919,186 | $759.32M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 3,935,302 | $150.01M | -19,301 | ↓ DEC |
STATE STREET CORPCIK 0000093751 | 2,250,920 | $85.81M | +518,905 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 1,818,665 | $69.33M | -254,123 | ↓ DEC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 1,739,003 | $66.29M | +435,973 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,717,076 | $65.45M | +1,717,076 | NEW |
RTW INVESTMENTS, LPCIK 0001493215 | 1,487,934 | $56.72M | +1 | ↑ INC |
TCG Crossover Management, LLCCIK 0001839948 | 1,445,538 | $55.10M | – | no_change |
Ikarian Capital, LLCCIK 0001778253 | 1,365,795 | $52.06M | +646,008 | ↑ INC |
Boxer Capital Management, LLCCIK 0002018299 | 1,361,000 | $51.88M | +225,000 | ↑ INC |
ICONIQ Capital, LLCCIK 0001569709 | 1,266,563 | $48.28M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 1,042,388 | $39.74M | +686,709 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,000,411 | $38.14M | +102,719 | ↑ INC |
SILVERARC CAPITAL MANAGEMENT, LLCCIK 0001816307 | 991,930 | $37.81M | -31,192 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 726,547 | $27.70M | +463,269 | ↑ INC |
Board of Trustees of The Leland Stanford Junior UniversityCIK 0001315828 | 691,767 | $26.37M | – | no_change |
Artisan Partners Limited PartnershipCIK 0001466153 | 690,322 | $26.32M | -146,184 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 515,864 | $19.66M | -183,908 | ↓ DEC |
Point72 Asset Management, L.P.CIK 0001603466 | 459,723 | $17.52M | -1,707,206 | ↓ DEC |
DIADEMA PARTNERS LPCIK 0002026172 | 440,062 | $16.78M | +410,462 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 436,329 | $16.63M | -37,467 | ↓ DEC |
NORTHERN TRUST CORPCIK 0000073124 | 391,349 | $14.92M | +57,681 | ↑ INC |
Squadron Capital Management LLCCIK 0002050709 | 380,000 | $14.49M | +88,290 | ↑ INC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 365,051 | $13.92M | +365,051 | NEW |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 356,270 | $13.58M | +183,049 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,717,076 | $65.45M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +869,171 | $77.74K |
T. Rowe Price Investment Management, Inc.↑ INC | +823,743 | $31.91K |
CITADEL ADVISORS LLC↑ INC | +686,709 | $39.74M |
Ikarian Capital, LLC↑ INC | +646,008 | $52.06M |
STATE STREET CORP↑ INC | +518,905 | $85.81M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +463,269 | $27.70M |
GOLDMAN SACHS GROUP INC↑ INC | +435,973 | $66.29M |
DIADEMA PARTNERS LP↑ INC | +410,462 | $16.78M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +365,051 | $13.92M |
| Filer | Δ Shares | Value |
|---|---|---|
Point72 Asset Management, L.P.↓ DEC | -1,707,206 | $17.52M |
BRAIDWELL LP↓ DEC | -254,123 | $69.33M |
Invesco Ltd.↓ DEC | -249,999 | $11.63M |
BOONE CAPITAL MANAGEMENT LLC↓ DEC | -222,498 | $10.72M |
MORGAN STANLEY↓ DEC | -183,908 | $19.66M |
PANAGORA ASSET MANAGEMENT INC↓ DEC | -151,001 | $1.13M |
Artisan Partners Limited Partnership↓ DEC | -146,184 | $26.32M |
BARCLAYS PLC↓ DEC | -113,029 | $430.95K |
FRED ALGER MANAGEMENT, LLC↓ DEC | -89,924 | $1.84M |
JACOBS LEVY EQUITY MANAGEMENT, INC↓ DEC | -86,291 | $1.56M |