| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Dec 18, 2025 | Lazar David E. | Chief Executive Officer | J | 368,614 | – | – |
| Nov 24, 2025 | Lazar David E. | Chief Executive Officer | A | 900,000 | – | – |
| Oct 23, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | S | 967 | $0.8200 | $792.00 |
| Oct 23, 2025 | Iwicki Mark T | Director | S | 154,894 | $0.8100 | $125.46K |
| Oct 22, 2025 | Kharabi Darius | CHIEF BUSINESS OFFICER | S | 20,806 | $0.8300 | $17.27K |
| Oct 22, 2025 | Brazzell Romulus K | SEE REMARKS | S | 46,748 | $0.8300 | $38.80K |
| Oct 22, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | S | 32,230 | $0.8300 | $26.75K |
| Oct 22, 2025 | Bazemore Todd | Director | S | 47,768 | $0.8300 | $39.65K |
| Oct 1, 2025 | BAKER BROS. ADVISORS LP | Other | S | 462,967 | $1.3838 | $640.65K |
| Oct 1, 2025 | BAKER BROS. ADVISORS LP | Other | S | 50,640 | $1.3838 | $70.08K |
| Sep 30, 2025 | BAKER BROS. ADVISORS LP | Other | S | 195,425 | $1.5959 | $311.88K |
| Sep 30, 2025 | BAKER BROS. ADVISORS LP | Other | S | 21,376 | $1.5959 | $34.11K |
| Aug 29, 2025 | Bazemore Todd | SEE REMARKS | A | 180,000 | $0.0000 | $0.00 |
| Jun 24, 2025 | Iwicki Mark T | Director | S | 13,227 | $4.0100 | $53.04K |
| Jun 24, 2025 | Brazzell Romulus K | SEE REMARKS | S | 5,251 | $4.0100 | $21.06K |
| Jun 24, 2025 | Bazemore Todd | SEE REMARKS | S | 4,058 | $4.0100 | $16.27K |
| Jun 24, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | S | 3,631 | $4.0100 | $14.56K |
| Jun 24, 2025 | Kharabi Darius | CHIEF BUSINESS OFFICER | S | 4,511 | $4.0100 | $18.09K |
| Jun 15, 2025 | KOVEN ANDREW I | Director | A | 6,850 | $0.0000 | $0.00 |
| Jun 15, 2025 | KOVEN ANDREW I | Director | A | 3,050 | $0.0000 | $0.00 |
| Jun 15, 2025 | Farid Marjan | Director | A | 5,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Farid Marjan | Director | A | 2,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Myers C. Daniel | Director | A | 5,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Myers C. Daniel | Director | A | 2,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | PERRY GREGORY D | Director | A | 5,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | PERRY GREGORY D | Director | A | 2,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Iwicki Mark T | Director | A | 5,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Iwicki Mark T | Director | A | 2,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Rosen Howard B | Director | A | 5,450 | $0.0000 | $0.00 |
| Jun 15, 2025 | Rosen Howard B | Director | A | 2,450 | $0.0000 | $0.00 |
| Jun 3, 2025 | Iwicki Mark T | Director | S | 10,866 | $3.7400 | $40.64K |
| Jun 3, 2025 | Brazzell Romulus K | SEE REMARKS | S | 3,687 | $3.7400 | $13.79K |
| Jun 3, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | S | 2,850 | $3.7400 | $10.66K |
| Jun 3, 2025 | Bazemore Todd | SEE REMARKS | S | 3,390 | $3.7400 | $12.68K |
| Jun 3, 2025 | Kharabi Darius | CHIEF BUSINESS OFFICER | S | 730 | $3.7400 | $2.73K |
| Jun 3, 2025 | Iwicki Mark T | Director | S | 10,866 | $3.7400 | $40.64K |
| Mar 7, 2025 | Bazemore Todd | SEE REMARKS | A | 45,200 | $0.0000 | $0.00 |
| Jan 6, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | A | 45,200 | $0.0000 | $0.00 |
| Jan 6, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | S | 1,706 | $7.6300 | $13.02K |
| Jan 6, 2025 | Reumuth Mary | CHIEF FINANCIAL OFFICER | A | 10,100 | $0.0000 | $0.00 |
| Jan 6, 2025 | Iwicki Mark T | CHIEF EXECUTIVE OFFICER | A | 99,500 | $0.0000 | $0.00 |
| Jan 6, 2025 | Iwicki Mark T | CHIEF EXECUTIVE OFFICER | S | 5,779 | $7.6300 | $44.09K |
| Jan 6, 2025 | Iwicki Mark T | CHIEF EXECUTIVE OFFICER | A | 22,100 | $0.0000 | $0.00 |
| Jan 6, 2025 | Bazemore Todd | SEE REMARKS | A | 45,200 | $0.0000 | $0.00 |
| Jan 6, 2025 | Bazemore Todd | SEE REMARKS | S | 1,993 | $7.6300 | $15.21K |
| Jan 6, 2025 | Bazemore Todd | SEE REMARKS | A | 10,100 | $0.0000 | $0.00 |
| Jan 6, 2025 | Brazzell Romulus K | SEE REMARKS | A | 45,200 | $0.0000 | $0.00 |
| Jan 6, 2025 | Brazzell Romulus K | SEE REMARKS | S | 2,446 | $7.6300 | $18.66K |
| Jan 6, 2025 | Brazzell Romulus K | SEE REMARKS | A | 10,100 | $0.0000 | $0.00 |
| Jan 6, 2025 | Kharabi Darius | CHIEF BUSINESS OFFICER | A | 45,200 | $0.0000 | $0.00 |