| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 19, 2026 | Berry Tamsin | Director | A | 50,000 | $0.0000 | $0.00 |
| May 19, 2026 | Elia Marc | Director, Other | A | 50,000 | $0.0000 | $0.00 |
| May 19, 2026 | BOLNO PAUL | Director | A | 32,876 | $0.0000 | $0.00 |
| May 19, 2026 | MCGUIRE TERRANCE | Director | A | 50,000 | $0.0000 | $0.00 |
| May 19, 2026 | MCLAUGHLIN KEVIN F | Director | A | 50,000 | $0.0000 | $0.00 |
| May 19, 2026 | Royan Ajay | Director | A | 50,000 | $0.0000 | $0.00 |
| Feb 18, 2026 | Andersen Jill | Chief Legal Officer, Secretary | S | 34,939 | $1.5778 | $55.13K |
| Feb 18, 2026 | Duke William E. | Chief Financial Officer | S | 20,964 | $1.5778 | $33.08K |
| Feb 18, 2026 | Lee Timothy Edward | Chief Commercial Officer | S | 20,964 | $1.5778 | $33.08K |
| Feb 18, 2026 | Allen Robert D. III | Chief Scientific Officer | S | 19,392 | $1.5778 | $30.60K |
| Feb 18, 2026 | Green Julie | Chief Human Resources Officer | S | 20,964 | $1.5778 | $33.08K |
| Feb 17, 2026 | Andersen Jill | Chief Legal Officer, Secretary | S | 32,771 | $1.5396 | $50.45K |
| Feb 17, 2026 | Duke William E. | Chief Financial Officer | S | 19,663 | $1.5396 | $30.27K |
| Feb 17, 2026 | Lee Timothy Edward | Chief Commercial Officer | S | 19,663 | $1.5396 | $30.27K |
| Feb 17, 2026 | Allen Robert D. III | Chief Scientific Officer | S | 18,189 | $1.5396 | $28.00K |
| Feb 17, 2026 | Green Julie | Chief Human Resources Officer | S | 19,663 | $1.5396 | $30.27K |
| Feb 15, 2026 | Andersen Jill | Chief Legal Officer, Secretary | M | 165,000 | $0.0000 | $0.00 |
| Feb 15, 2026 | Andersen Jill | Chief Legal Officer, Secretary | M | 165,000 | – | – |
| Feb 15, 2026 | Duke William E. | Chief Financial Officer | M | 99,000 | $0.0000 | $0.00 |
| Feb 15, 2026 | Lee Timothy Edward | Chief Commercial Officer | M | 99,000 | $0.0000 | $0.00 |
| Feb 15, 2026 | Lee Timothy Edward | Chief Commercial Officer | M | 99,000 | – | – |
| Feb 15, 2026 | Duke William E. | Chief Financial Officer | M | 99,000 | – | – |
| Feb 15, 2026 | Allen Robert D. III | Chief Scientific Officer | M | 99,000 | $0.0000 | $0.00 |
| Feb 15, 2026 | Green Julie | Chief Human Resources Officer | M | 99,000 | $0.0000 | $0.00 |
| Feb 15, 2026 | Allen Robert D. III | Chief Scientific Officer | M | 99,000 | – | – |
| Feb 15, 2026 | Green Julie | Chief Human Resources Officer | M | 99,000 | – | – |
| Jan 29, 2026 | Allen Robert D. III | Chief Scientific Officer | A | 625,000 | $0.0000 | $0.00 |
| Jan 29, 2026 | Andersen Jill | Chief Legal Officer, Secretary | A | 820,000 | $0.0000 | $0.00 |
| Jan 29, 2026 | Lee Timothy Edward | Chief Commercial Officer | A | 675,000 | $0.0000 | $0.00 |
| Jan 29, 2026 | Green Julie | Chief Human Resources Officer | A | 675,000 | $0.0000 | $0.00 |
| Jan 29, 2026 | Duke William E. | Chief Financial Officer | A | 625,000 | $0.0000 | $0.00 |
| Nov 19, 2025 | MCLAUGHLIN KEVIN F | Director | P | 50,000 | $2.5000 | $125.00K |
| Sep 22, 2025 | BOLNO PAUL | Director | A | 100,000 | $0.0000 | $0.00 |
| Aug 19, 2025 | Allen Robert D. III | Chief Scientific Officer | S | 27,420 | $0.5666 | $15.54K |
| Aug 19, 2025 | Andersen Jill | Chief Legal Officer, Secretary | S | 49,402 | $0.5666 | $27.99K |
| Aug 19, 2025 | Duke William E. | Chief Financial Officer | S | 29,643 | $0.5666 | $16.80K |
| Aug 19, 2025 | Green Julie | Chief Human Resources Officer | S | 29,643 | $0.5666 | $16.80K |
| Aug 19, 2025 | Lee Timothy Edward | Chief Commercial Officer | S | 29,643 | $0.5666 | $16.80K |
| Aug 18, 2025 | Allen Robert D. III | Chief Scientific Officer | S | 18,512 | $0.6502 | $12.04K |
| Aug 18, 2025 | Andersen Jill | Chief Legal Officer, Secretary | S | 33,352 | $0.6502 | $21.68K |
| Aug 18, 2025 | Duke William E. | Chief Financial Officer | S | 20,013 | $0.6502 | $13.01K |
| Aug 18, 2025 | Green Julie | Chief Human Resources Officer | S | 20,013 | $0.6502 | $13.01K |
| Aug 18, 2025 | Lee Timothy Edward | Chief Commercial Officer | S | 20,013 | $0.6502 | $13.01K |
| Aug 15, 2025 | Allen Robert D. III | Chief Scientific Officer | M | 99,000 | $0.0000 | $0.00 |
| Aug 15, 2025 | Allen Robert D. III | Chief Scientific Officer | M | 99,000 | – | – |
| Aug 15, 2025 | Andersen Jill | Chief Legal Officer, Secretary | M | 165,000 | $0.0000 | $0.00 |
| Aug 15, 2025 | Andersen Jill | Chief Legal Officer, Secretary | M | 165,000 | – | – |
| Aug 15, 2025 | Duke William E. | Chief Financial Officer | M | 99,000 | $0.0000 | $0.00 |
| Aug 15, 2025 | Duke William E. | Chief Financial Officer | M | 99,000 | – | – |
| Aug 15, 2025 | Green Julie | Chief Human Resources Officer | M | 99,000 | $0.0000 | $0.00 |