First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Affinity Asset Advisors, LLCCIK 0001773195 | 3,107,200 | $5.90M | +1,050,000 | ↑ INC |
Frazier Life Sciences Management, L.P.CIK 0001892134 | 1,953,467 | $3.71M | – | no_change |
EcoR1 Capital, LLCCIK 0001587114 | 1,583,000 | $3.01M | -645,000 | ↓ DEC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 1,549,850 | $2.94M | +1,549,850 | NEW |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,088,299 | $2.07M | +1,088,299 | NEW |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 1,010,955 | $1.92M | -85,224 | ↓ DEC |
Ikarian Capital, LLCCIK 0001778253 | 957,062 | $1.82M | – | no_change |
CITADEL ADVISORS LLCCIK 0001423053 | 956,429 | $1.82M | +824,471 | ↑ INC |
Sio Capital Management, LLCCIK 0001482416 | 904,268 | $1.72M | +164,268 | ↑ INC |
MARSHALL WACE, LLPCIK 0001318757 | 620,602 | $1.18M | +499,316 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 469,878 | $892.77K | +64,347 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 412,725 | $784.18K | +368,254 | ↑ INC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 408,858 | $776.83K | -47,475 | ↓ DEC |
Walleye Capital LLCCIK 0001758720 | 388,554 | $738.25K | +190,179 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 387,567 | $736.60K | +164,957 | ↑ INC |
NOESIS CAPITAL MANGEMENT CORPCIK 0001262677 | 311,500 | $591.85K | +87,300 | ↑ INC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 290,413 | $551.78K | +174,620 | ↑ INC |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 254,412 | $483.38K | – | no_change |
SILVERARC CAPITAL MANAGEMENT, LLCCIK 0001816307 | 226,000 | $429.40K | +120,000 | ↑ INC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 205,015 | $389.53K | +205,015 | NEW |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 200,212 | $380.40K | +200,212 | NEW |
DAFNA Capital Management LLCCIK 0001389933 | 193,638 | $367.91K | +193,638 | NEW |
STATE STREET CORPCIK 0000093751 | 141,199 | $268.28K | +68,300 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 131,215 | $249.31K | +88,488 | ↑ INC |
NORTHERN TRUST CORPCIK 0000073124 | 77,324 | $146.92K | +37,010 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
MILLENNIUM MANAGEMENT LLCNEW | +1,549,850 | $2.94M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,088,299 | $2.07M |
Affinity Asset Advisors, LLC↑ INC | +1,050,000 | $5.90M |
CITADEL ADVISORS LLC↑ INC | +824,471 | $1.82M |
MARSHALL WACE, LLP↑ INC | +499,316 | $1.18M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↑ INC | +368,254 | $784.18K |
VANGUARD FIDUCIARY TRUST CONEW | +205,015 | $389.53K |
GOLDMAN SACHS GROUP INCNEW | +200,212 | $380.40K |
DAFNA Capital Management LLCNEW | +193,638 | $367.91K |
Walleye Capital LLC↑ INC | +190,179 | $738.25K |
| Filer | Δ Shares | Value |
|---|---|---|
Lynx1 Capital Management LP↓ DEC | -987,821 | $129.34K |
EcoR1 Capital, LLC↓ DEC | -645,000 | $3.01M |
UBS Group AG↓ DEC | -124,383 | $4.13K |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -85,224 | $1.92M |
TWO SIGMA INVESTMENTS, LP↓ DEC | -47,475 | $776.83K |
Virtu Financial LLC↓ DEC | -31,078 | $21.00 |
CITIGROUP INC↓ DEC | -3,673 | $2.61K |
PFG Investments, LLC↓ DEC | -1,500 | $38.00K |
Vanguard Personalized Indexing Management, LLC↓ DEC | -311 | $23.14K |