| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 11, 2026 | Dougan Brady W | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Brown Emery N. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Bamforth John Philip | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Seimetz Diane | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Green Charles Bruce | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Jones Keith Anthony | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Sebelius Kathleen | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Niklason Laura E | President, CEO and Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Wallace Max N. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Constantino Michael T. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Windham-Bannister Susan Richards | Director | A | 80,000 | $0.0000 | $0.00 |
| May 19, 2026 | Sebelius Kathleen | Director | P | 56,818 | $0.8800 | $50.00K |
| May 18, 2026 | Parikh Shamik J | Chief Medical Officer | S | 45,887 | $0.8967 | $41.15K |
| May 18, 2026 | Sander Dale A. | CFO and Chief Corp. Dev. Off | S | 45,887 | $0.8967 | $41.15K |
| May 18, 2026 | Constantino Michael T. | Director | P | 11,000 | $0.8945 | $9.84K |
| Nov 16, 2025 | Niklason Laura E | President, CEO and Director | A | 311,100 | $0.0000 | $0.00 |
| Nov 16, 2025 | Parikh Shamik J | Chief Medical Officer | A | 311,100 | $0.0000 | $0.00 |
| Nov 16, 2025 | Dougan Brady W | Director | A | 311,100 | $0.0000 | $0.00 |
| Nov 16, 2025 | Sander Dale A. | CFO and Chief Corp. Deve. Off. | A | 311,100 | $0.0000 | $0.00 |
| Aug 20, 2025 | Niklason Laura E | President, CEO and Director | S | 591,685 | $1.5800 | $934.86K |
| Aug 20, 2025 | Dougan Brady W | Director | S | 591,685 | $1.5800 | $934.86K |
| Aug 19, 2025 | Niklason Laura E | President, CEO and Director | S | 1,100,000 | $1.6300 | $1.79M |
| Aug 19, 2025 | Dougan Brady W | Director | S | 1,100,000 | $1.6300 | $1.79M |
| Aug 18, 2025 | Niklason Laura E | President, CEO and Director | S | 549,360 | $1.8300 | $1.01M |
| Aug 18, 2025 | Dougan Brady W | Director | S | 549,360 | $1.8300 | $1.01M |
| Jun 12, 2025 | Seimetz Diane | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Sebelius Kathleen | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Constantino Michael T. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Bamforth John Philip | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Green Charles Bruce | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Dougan Brady W | Director | A | 0 | $0.0000 | $0.00 |
| Jun 12, 2025 | Niklason Laura E | President, CEO and Director | A | 0 | $0.0000 | $0.00 |
| Jun 12, 2025 | Wallace Max N. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Windham-Bannister Susan Richards | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Jones Keith Anthony | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Brown Emery N. | Director | A | 80,000 | $0.0000 | $0.00 |
| Jun 12, 2025 | Pope Todd | Director | A | 80,000 | $0.0000 | $0.00 |
| Apr 14, 2025 | Scheessele William John | Chief Commercial Officer | P | 6,493 | $1.5400 | $10.00K |
| Apr 10, 2025 | Parikh Shamik J | Chief Medical Officer | P | 7,500 | $1.5500 | $11.63K |
| Apr 10, 2025 | Sander Dale A. | CFO and Chief Corp. Deve. Off. | P | 20,000 | $1.5300 | $30.60K |
| Apr 8, 2025 | Green Charles Bruce | Director | P | 6,000 | $1.2900 | $7.74K |
| Apr 8, 2025 | Sebelius Kathleen | Director | P | 50,000 | $1.3200 | $66.00K |
| Apr 7, 2025 | Constantino Michael T. | Director | P | 16,000 | $1.2600 | $20.16K |
| Jan 21, 2025 | Parikh Shamik J | Chief Medical Officer | A | 283,101 | $0.0000 | $0.00 |
| Jan 21, 2025 | Sander Dale A. | CFO and Chief Corp. Deve. Off. | A | 283,101 | $0.0000 | $0.00 |
| Jan 21, 2025 | Niklason Laura E | President, CEO and Director | A | 1,130,311 | $0.0000 | $0.00 |
| Jan 21, 2025 | Prichard Heather Ledbetter | Chief Operating Officer | A | 283,101 | $0.0000 | $0.00 |
| Jan 21, 2025 | Scheessele William John | Chief Commercial Officer | A | 283,101 | $0.0000 | $0.00 |
| Jan 21, 2025 | Cao Yang | Chief Regulatory Officer | A | 283,101 | $0.0000 | $0.00 |
| Jan 21, 2025 | Dougan Brady W | Director | A | 1,130,311 | $0.0000 | $0.00 |