First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Venrock Adviser, LLCCIK 0001615982 | 3,851,654 | $18.49M | +11,404 | ↑ INC |
ORBIMED ADVISORS LLCCIK 0001055951 | 3,832,843 | $18.40M | -7,657 | ↓ DEC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 2,415,841 | $11.60M | +1,387,292 | ↑ INC |
ACORN CAPITAL ADVISORS, LLCCIK 0002054410 | 1,540,266 | $7.39M | -32,757 | ↓ DEC |
Rosalind Advisors, Inc.CIK 0001622627 | 1,531,814 | $7.35M | -125,726 | ↓ DEC |
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891 | 1,410,815 | $6.77M | +153,815 | ↑ INC |
Deep Track Capital, LPCIK 0001856083 | 1,313,137 | $6.30M | -541,118 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 1,025,318 | $4.92M | -274,438 | ↓ DEC |
SPHERA FUNDS MANAGEMENT LTD.CIK 0001496201 | 987,090 | $4.74M | +161,514 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 915,647 | $4.40M | +40,070 | ↑ INC |
DCF Advisers, LLCCIK 0001802493 | 691,988 | $3.32M | -83,600 | ↓ DEC |
Boxer Capital Management, LLCCIK 0002018299 | 640,000 | $3.07M | -75,000 | ↓ DEC |
DAFNA Capital Management LLCCIK 0001389933 | 498,361 | $2.39M | +43,343 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 498,325 | $2.39M | -34,505 | ↓ DEC |
Nan Fung Group Holdings LtdCIK 0001782539 | 460,000 | $2.21M | – | no_change |
Knott David M JrCIK 0001892770 | 350,000 | $1.68M | +64,818 | ↑ INC |
UBS Group AGCIK 0001610520 | 238,302 | $1.14M | +4,588 | ↑ INC |
AdvisorShares Investments LLCCIK 0001425930 | 195,604 | $938.90K | +97,546 | ↑ INC |
Caption Management, LLCCIK 0001706766 | 165,000 | $792.00K | +114,947 | ↑ INC |
ROYCE & ASSOCIATES LPCIK 0000906304 | 155,050 | $744.24K | +155,050 | NEW |
Pale Fire Capital SECIK 0001922318 | 153,505 | $736.82K | – | no_change |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 141,588 | $679.62K | +3,657 | ↑ INC |
Stonepine Capital Management, LLCCIK 0001440771 | 134,060 | $643.49K | -205,842 | ↓ DEC |
Ikarian Capital, LLCCIK 0001778253 | 132,153 | $634.33K | – | no_change |
JANE STREET GROUP, LLCCIK 0001595888 | 106,349 | $510.48K | +7,315 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
MILLENNIUM MANAGEMENT LLC↑ INC | +1,387,292 | $11.60M |
HRT FINANCIAL LPNEW | +187,052 | $897.00 |
SPHERA FUNDS MANAGEMENT LTD.↑ INC | +161,514 | $4.74M |
ROYCE & ASSOCIATES LPNEW | +155,050 | $744.24K |
EVENTIDE ASSET MANAGEMENT, LLC↑ INC | +153,815 | $6.77M |
Caption Management, LLC↑ INC | +114,947 | $792.00K |
AdvisorShares Investments LLC↑ INC | +97,546 | $938.90K |
Knott David M Jr↑ INC | +64,818 | $1.68M |
DAFNA Capital Management LLC↑ INC | +43,343 | $2.39M |
CITADEL ADVISORS LLC↑ INC | +40,070 | $4.40M |
| Filer | Δ Shares | Value |
|---|---|---|
Point72 Asset Management, L.P.↓ DEC | -4,412,875 | $94.48K |
Deep Track Capital, LP↓ DEC | -541,118 | $6.30M |
MORGAN STANLEY↓ DEC | -274,438 | $4.92M |
PEAK6 LLC↓ DEC | -220,910 | $300.47K |
ADAR1 Capital Management, LLC↓ DEC | -207,112 | $150.13K |
Stonepine Capital Management, LLC↓ DEC | -205,842 | $643.49K |
Rosalind Advisors, Inc.↓ DEC | -125,726 | $7.35M |
DCF Advisers, LLC↓ DEC | -83,600 | $3.32M |
Boxer Capital Management, LLC↓ DEC | -75,000 | $3.07M |
Jump Financial, LLC↓ DEC | -37,761 | $86.40K |