First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
FMR LLCCIK 0000315066 | 8,403,449 | $405.05M | -308,802 | ↓ DEC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 7,260,287 | $349.95M | +138,303 | ↑ INC |
Avoro Capital Advisors LLCCIK 0001633313 | 6,555,555 | $315.98M | – | no_change |
Deep Track Capital, LPCIK 0001856083 | 4,279,848 | $206.29M | +168,066 | ↑ INC |
BVF INC/ILCIK 0001056807 | 3,459,358 | $166.74M | -19,664 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 2,305,457 | $111.12M | +217,623 | ↑ INC |
PRINCIPAL FINANCIAL GROUP INCCIK 0001126328 | 1,753,764 | $84.53M | +469,554 | ↑ INC |
DRIEHAUS CAPITAL MANAGEMENT LLCCIK 0000938206 | 1,577,356 | $76.03M | -65,088 | ↓ DEC |
ORBIMED ADVISORS LLCCIK 0001055951 | 1,475,403 | $71.11M | +313,600 | ↑ INC |
AMERICAN CENTURY COMPANIES INCCIK 0000748054 | 1,438,031 | $69.31M | +931,072 | ↑ INC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 1,432,529 | $69.05M | – | no_change |
Siren, L.L.C.CIK 0002005245 | 1,328,698 | $64.04M | +250,000 | ↑ INC |
Casdin Capital, LLCCIK 0001534261 | 1,175,000 | $56.63M | – | no_change |
CAPITOLIS LIQUID GLOBAL MARKETS LLCCIK 0002094379 | 1,151,300 | $55.49M | +273,000 | ↑ INC |
ALLIANCEBERNSTEIN L.P.CIK 0001109448 | 638,813 | $44.43M | -210,038 | ↓ DEC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 767,993 | $37.02M | – | no_change |
PACIFIC HEIGHTS ASSET MANAGEMENT LLCCIK 0001323414 | 750,000 | $36.15M | +50,000 | ↑ INC |
Rock Springs Capital Management LPCIK 0001595725 | 640,217 | $30.86M | -108,019 | ↓ DEC |
Paradigm Biocapital Advisors LPCIK 0001855655 | 545,287 | $26.28M | +172,418 | ↑ INC |
FRANKLIN RESOURCES INCCIK 0000038777 | 531,595 | $25.62M | -338,987 | ↓ DEC |
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUNDCIK 0001535845 | 467,800 | $22.55M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 441,975 | $21.30M | +11,893 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 434,043 | $20.92M | +36,211 | ↑ INC |
Aberdeen Group plcCIK 0001716774 | 391,809 | $18.89M | +126,940 | ↑ INC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 380,042 | $18.32M | +11,243 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
AMERICAN CENTURY COMPANIES INC↑ INC | +931,072 | $69.31M |
PRINCIPAL FINANCIAL GROUP INC↑ INC | +469,554 | $84.53M |
PRICE T ROWE ASSOCIATES INC /MD/↑ INC | +329,558 | $96.43K |
ORBIMED ADVISORS LLC↑ INC | +313,600 | $71.11M |
CAPITOLIS LIQUID GLOBAL MARKETS LLC↑ INC | +273,000 | $55.49M |
Siren, L.L.C.↑ INC | +250,000 | $64.04M |
SEB Asset Management ABNEW | +245,043 | $11.81M |
Pentwater Capital Management LPNEW | +245,000 | $11.81M |
MORGAN STANLEY↑ INC | +217,623 | $111.12M |
JPMORGAN CHASE & CO↑ INC | +199,847 | $9.35M |
| Filer | Δ Shares | Value |
|---|---|---|
Cormorant Asset Management, LP↓ DEC | -881,373 | $8.44M |
CITADEL ADVISORS LLC↓ DEC | -792,218 | $5.51M |
TCG Crossover Management, LLC↓ DEC | -780,446 | $6.77M |
DEUTSCHE BANK AG\↓ DEC | -509,295 | $16.00M |
Avidity Partners Management LP↓ DEC | -382,900 | $1.99M |
FRANKLIN RESOURCES INC↓ DEC | -338,987 | $25.62M |
FMR LLC↓ DEC | -308,802 | $405.05M |
ALLIANCEBERNSTEIN L.P.↓ DEC | -210,038 | $44.43M |
Monashee Investment Management LLC↓ DEC | -175,000 | $2.41M |
STEMPOINT CAPITAL LP↓ DEC | -150,806 | $9.65M |