| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 1, 2026 | Smither John W | Director | S | 12,000 | $2.9082 | $34.90K |
| Jun 16, 2026 | Smither John W | Director | A | 31,566 | $0.0000 | $0.00 |
| Jun 16, 2026 | Smither John W | Director | A | 28,409 | $0.0000 | $0.00 |
| Jun 16, 2026 | Yu Yong | Chief Scientific Officer | A | 119,318 | $0.0000 | $0.00 |
| Jun 16, 2026 | Mirabelli Mary | Director | A | 31,566 | $0.0000 | $0.00 |
| Jun 16, 2026 | Mirabelli Mary | Director | A | 28,409 | $0.0000 | $0.00 |
| Jun 16, 2026 | Thomas John | Director | A | 31,566 | $0.0000 | $0.00 |
| Jun 16, 2026 | Thomas John | Director | A | 28,409 | $0.0000 | $0.00 |
| Jun 16, 2026 | Zindrick Thomas | President and CEO | A | 730,601 | $0.0000 | $0.00 |
| Jun 16, 2026 | Tyree James L | Director | A | 31,566 | $0.0000 | $0.00 |
| Jun 16, 2026 | Tyree James L | Director | A | 28,409 | $0.0000 | $0.00 |
| Jun 16, 2026 | Cappello Joseph | Chief Technical Officer | A | 174,841 | $0.0000 | $0.00 |
| Jun 16, 2026 | Groen Eric | General Counsel | A | 233,957 | $0.0000 | $0.00 |
| Jun 16, 2026 | Pulisic Matthew | Chief Financial Officer | A | 278,906 | $0.0000 | $0.00 |
| Jun 3, 2026 | Smalling Ralph | Head of Regulatory | S | 192 | $2.9300 | $562.00 |
| Jun 1, 2026 | Thomas John | Director | S | 10,000 | $2.9801 | $29.80K |
| May 11, 2026 | Yu Yong | Chief Scientific Officer | S | 605 | $2.9726 | $1.80K |
| May 11, 2026 | Cappello Joseph | Chief Technical Officer | S | 605 | $2.9742 | $1.80K |
| May 11, 2026 | Smalling Ralph | Head of Regulatory | S | 270 | $2.9796 | $804.00 |
| May 11, 2026 | Zindrick Thomas | President and CEO | S | 2,798 | $2.9398 | $8.22K |
| Mar 25, 2026 | Smalling Ralph | Head of Regulatory | S | 240 | $2.5100 | $602.00 |
| Mar 24, 2026 | Yu Yong | SVP, Clinical Development | S | 906 | $2.4200 | $2.19K |
| Mar 24, 2026 | Cappello Joseph | Chief Technical Officer | S | 906 | $2.4200 | $2.19K |
| Mar 24, 2026 | Zindrick Thomas | President and CEO | S | 3,582 | $2.4200 | $8.67K |
| Mar 24, 2026 | Smalling Ralph | Head of Regulatory | S | 345 | $2.4200 | $834.00 |
| Mar 2, 2026 | Thomas John | Director | S | 10,000 | $2.8957 | $28.96K |
| Jan 2, 2026 | Litten Jason | Chief Medical Officer | A | 275,000 | $0.0000 | $0.00 |
| Dec 5, 2025 | Smalling Ralph | Head of Regulatory | S | 165 | $4.6900 | $773.00 |
| Dec 1, 2025 | Thomas John | Director | S | 10,000 | $5.0008 | $50.01K |
| Nov 17, 2025 | Smalling Ralph | Head of Regulatory | S | 343 | $5.3694 | $1.84K |
| Nov 17, 2025 | Cappello Joseph | Chief Technical Officer | S | 973 | $5.3694 | $5.22K |
| Nov 17, 2025 | Zindrick Thomas | President and CEO | S | 4,509 | $5.3694 | $24.21K |
| Nov 17, 2025 | Yu Yong | SVP, Clinical Development | S | 973 | $5.3694 | $5.22K |
| Sep 3, 2025 | Smalling Ralph | Head of Regulatory | S | 580 | $3.3590 | $1.95K |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | A | 65,000 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | D | 65,000 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | A | 13,333 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | D | 13,333 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | A | 80,000 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | D | 80,000 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | A | 16,666 | – | – |
| Sep 1, 2025 | Cappello Joseph | Chief Technical Officer | D | 16,666 | – | – |
| Sep 1, 2025 | Smalling Ralph | Head of Regulatory | A | 8,333 | – | – |
| Sep 1, 2025 | Smalling Ralph | Head of Regulatory | D | 8,333 | – | – |
| Sep 1, 2025 | Smalling Ralph | Head of Regulatory | A | 10,000 | $0.0000 | $0.00 |
| Sep 1, 2025 | Yu Yong | SVP, Clinical Development | A | 65,000 | – | – |
| Sep 1, 2025 | Yu Yong | SVP, Clinical Development | D | 65,000 | – | – |
| Sep 1, 2025 | Yu Yong | SVP, Clinical Development | A | 207,652 | – | – |
| Sep 1, 2025 | Yu Yong | SVP, Clinical Development | D | 207,652 | – | – |
| Sep 1, 2025 | Zindrick Thomas | President and CEO | A | 250,000 | – | – |