| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Mar 2, 2026 | Bowie Alfred Lloyd Jr. | Chief Financial Officer | A | 67,044 | $0.0000 | $0.00 |
| Mar 2, 2026 | Baynes Roy D. | Chief Medical Officer | A | 134,088 | $0.0000 | $0.00 |
| Mar 2, 2026 | Thorner Benjamin Bruno | See Remarks | A | 67,044 | $0.0000 | $0.00 |
| Mar 2, 2026 | PERLMUTTER ROGER M | See remarks | A | 268,176 | $0.0000 | $0.00 |
| Mar 2, 2026 | FRAZIER KENNETH C | Director | A | 25,873 | $0.0000 | $0.00 |
| Mar 2, 2026 | Huffines Robert Luther | Director | A | 25,873 | $0.0000 | $0.00 |
| Mar 2, 2026 | Klobuchar Michael A | Chief Operating Officer | A | 87,157 | $0.0000 | $0.00 |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 1,376,566 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 194,510 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 40,677 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 472,822 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 709,234 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 71,190 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 106,785 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 1,376,566 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 335,521 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 194,510 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 1,046,827 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 1,340,878 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 40,677 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 2,155,765 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 472,822 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 1,151,540 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 709,234 | – | – |
| Feb 6, 2026 | Lux Venture Partners V, LLC | 10% Owner | C | 2,387,705 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 71,190 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 106,785 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 335,521 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 1,046,827 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 1,340,878 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 2,155,765 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 1,151,540 | – | – |
| Feb 6, 2026 | Wolfe Josh | Director, 10% Owner | C | 2,387,705 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 688,283 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 3,785 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 110,928 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 47,898 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 1,403,568 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 44,249 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 1,296,629 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | P | 630,881 | $18.0000 | $11.36M |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | P | 49,556 | $18.0000 | $892.01K |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | P | 1,437,323 | $18.0000 | $25.87M |
| Feb 6, 2026 | PERLMUTTER ROGER M | See remarks | C | 114,714 | – | – |
| Feb 6, 2026 | PERLMUTTER ROGER M | See remarks | C | 170,143 | – | – |
| Feb 6, 2026 | PERLMUTTER ROGER M | See remarks | C | 284,857 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 688,283 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 3,785 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 47,898 | – | – |
| Feb 6, 2026 | Column Group IV GP, LP | 10% Owner | C | 44,249 | – | – |