First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Cormorant Asset Management, LPCIK 0001583977 | 1,059,331 | $77.30M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 621,933 | $45.38M | +227,890 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 557,172 | $40.66M | +55,555 | ↑ INC |
BRAIDWELL LPCIK 0001920938 | 539,708 | $39.38M | +215,350 | ↑ INC |
Vestal Point Capital, LPCIK 0001974915 | 492,319 | $35.92M | +492,319 | NEW |
DRIEHAUS CAPITAL MANAGEMENT LLCCIK 0000938206 | 432,515 | $31.56M | +162,874 | ↑ INC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 377,544 | $27.55M | -71,746 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 297,158 | $21.68M | +71,746 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 283,000 | $20.65M | +283,000 | NEW |
GREAT POINT PARTNERS LLCCIK 0001281446 | 220,000 | $16.05M | +220,000 | NEW |
MPM BioImpact LLCCIK 0001687078 | 212,175 | $15.48M | -17,972 | ↓ DEC |
Ikarian Capital, LLCCIK 0001778253 | 166,647 | $12.16M | +7,226 | ↑ INC |
WELLINGTON MANAGEMENT GROUP LLPCIK 0000902219 | 136,677 | $9.97M | +122,989 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 132,764 | $9.69M | +642 | ↑ INC |
EVENTIDE ASSET MANAGEMENT, LLCCIK 0001442891 | 130,013 | $9.49M | +27,000 | ↑ INC |
SEVEN GRAND MANAGERS, LLCCIK 0001909126 | 120,000 | $8.76M | +70,000 | ↑ INC |
ACUTA CAPITAL PARTNERS, LLCCIK 0001582844 | 111,996 | $8.17M | +27,519 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 108,239 | $7.90M | +30,961 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 88,716 | $6.47M | +25,170 | ↑ INC |
Sio Capital Management, LLCCIK 0001482416 | 86,083 | $6.28M | +4,200 | ↑ INC |
GOLDMAN SACHS GROUP INCCIK 0000886982 | 74,369 | $5.43M | +25,822 | ↑ INC |
B Group, Inc.CIK 0002043476 | 67,500 | $4.93M | +67,500 | NEW |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 60,482 | $4.41M | +60,482 | NEW |
Walleye Capital LLCCIK 0001758720 | 53,706 | $3.92M | +27,880 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 52,832 | $3.86M | -141,605 | ↓ DEC |
| Filer | Δ Shares | Value |
|---|---|---|
Vestal Point Capital, LPNEW | +492,319 | $35.92M |
DEERFIELD MANAGEMENT COMPANY, L.P.NEW | +283,000 | $20.65M |
BlackRock, Inc.↑ INC | +227,890 | $45.38M |
GREAT POINT PARTNERS LLCNEW | +220,000 | $16.05M |
BRAIDWELL LP↑ INC | +215,350 | $39.38M |
DRIEHAUS CAPITAL MANAGEMENT LLC↑ INC | +162,874 | $31.56M |
WELLINGTON MANAGEMENT GROUP LLP↑ INC | +122,989 | $9.97M |
BALYASNY ASSET MANAGEMENT L.P.↑ INC | +71,746 | $21.68M |
SEVEN GRAND MANAGERS, LLC↑ INC | +70,000 | $8.76M |
B Group, Inc.NEW | +67,500 | $4.93M |
| Filer | Δ Shares | Value |
|---|---|---|
MILLENNIUM MANAGEMENT LLC↓ DEC | -141,605 | $3.86M |
PERCEPTIVE ADVISORS LLC↓ DEC | -71,746 | $27.55M |
SUPERSTRING CAPITAL MANAGEMENT LP↓ DEC | -33,967 | $971.30K |
BNP PARIBAS FINANCIAL MARKETS↓ DEC | -24,105 | $114.64K |
MPM BioImpact LLC↓ DEC | -17,972 | $15.48M |
BARCLAYS PLC↓ DEC | -6,583 | $224.53K |
WELLS FARGO & COMPANY/MN↓ DEC | -2,991 | $184.76K |
JANE STREET GROUP, LLC↓ DEC | -2,618 | $467.01K |
PLATINUM INVESTMENT MANAGEMENT LTD↓ DEC | -2,603 | $1.40M |
UBS Group AG↓ DEC | -533 | $969.04K |