| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 8, 2026 | Stengone Carmine N. | CEO and President | M | 2,500 | $0.0000 | $0.00 |
| Jul 8, 2026 | Stengone Carmine N. | CEO and President | S | 2,500 | $16.0000 | $40.00K |
| Jul 8, 2026 | Stengone Carmine N. | CEO and President | M | 2,500 | $1.0100 | $2.52K |
| Jul 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 4,183 | $0.0000 | $0.00 |
| Jul 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 2,501 | $16.2369 | $40.61K |
| Jul 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 5,852 | $15.6667 | $91.68K |
| Jul 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 4,183 | $1.0100 | $4.22K |
| Jun 30, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 28,826 | $0.0000 | $0.00 |
| Jun 30, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 28,826 | $16.0372 | $462.29K |
| Jun 30, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 28,826 | $1.0100 | $29.11K |
| Jun 30, 2026 | Stengone Carmine N. | CEO and President | M | 2,500 | $0.0000 | $0.00 |
| Jun 30, 2026 | Stengone Carmine N. | CEO and President | M | 7,500 | $0.0000 | $0.00 |
| Jun 30, 2026 | Stengone Carmine N. | CEO and President | S | 10,000 | $16.0080 | $160.08K |
| Jun 30, 2026 | Stengone Carmine N. | CEO and President | M | 2,500 | $1.2600 | $3.15K |
| Jun 30, 2026 | Stengone Carmine N. | CEO and President | M | 7,500 | $1.0100 | $7.58K |
| Jun 30, 2026 | Watkins Tim | CMO & Head of Development | M | 10,833 | $0.0000 | $0.00 |
| Jun 30, 2026 | Watkins Tim | CMO & Head of Development | S | 10,833 | $16.0242 | $173.59K |
| Jun 30, 2026 | Watkins Tim | CMO & Head of Development | M | 10,833 | $4.5000 | $48.75K |
| Jun 26, 2026 | Boyce Sarah | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Ignelzi Troy A. | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Ware Olivia C | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Brady Todd R. | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Schimmelpennink Evert B. | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Lyons-Williams Lori | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 26, 2026 | Miralles Gines Diego | Director | A | 19,000 | $0.0000 | $0.00 |
| Jun 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 4,170 | $13.1564 | $54.86K |
| May 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 300 | $13.8400 | $4.15K |
| May 1, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 3,870 | $13.0600 | $50.54K |
| Apr 6, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 4,170 | $13.4326 | $56.01K |
| Mar 2, 2026 | Watkins Tim | CMO & Head of Development | M | 3,611 | $0.0000 | $0.00 |
| Mar 2, 2026 | Watkins Tim | CMO & Head of Development | S | 3,611 | $15.0153 | $54.22K |
| Mar 2, 2026 | Watkins Tim | CMO & Head of Development | M | 3,611 | $4.5000 | $16.25K |
| Mar 2, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 4,170 | $15.0084 | $62.59K |
| Feb 25, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 3,824 | $0.0000 | $0.00 |
| Feb 25, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 3,824 | $16.0115 | $61.23K |
| Feb 25, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 3,824 | $1.0100 | $3.86K |
| Feb 25, 2026 | Stengone Carmine N. | CEO and President | M | 2,700 | $0.0000 | $0.00 |
| Feb 25, 2026 | Stengone Carmine N. | CEO and President | S | 2,700 | $16.0155 | $43.24K |
| Feb 25, 2026 | Stengone Carmine N. | CEO and President | M | 2,700 | $1.2600 | $3.40K |
| Feb 24, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 4,300 | $0.0000 | $0.00 |
| Feb 24, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 4,300 | $16.0316 | $68.94K |
| Feb 24, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 4,300 | $1.0100 | $4.34K |
| Feb 24, 2026 | Stengone Carmine N. | CEO and President | M | 4,400 | $0.0000 | $0.00 |
| Feb 24, 2026 | Stengone Carmine N. | CEO and President | S | 4,400 | $16.0195 | $70.48K |
| Feb 24, 2026 | Stengone Carmine N. | CEO and President | M | 4,400 | $1.2600 | $5.54K |
| Feb 19, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 100 | $0.0000 | $0.00 |
| Feb 19, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 100 | $16.0000 | $1.60K |
| Feb 19, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 100 | $1.0100 | $101.00 |
| Feb 11, 2026 | Lorrain Daniel S. | Chief Scientific Officer | M | 400 | $0.0000 | $0.00 |
| Feb 11, 2026 | Lorrain Daniel S. | Chief Scientific Officer | S | 400 | $16.0000 | $6.40K |