First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Sofinnova Investments, Inc.CIK 0001631134 | 137,721 | $556.39K | – | no_change |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 77,225 | $311.99K | +22,200 | ↑ INC |
Vivo Capital, LLCCIK 0001674712 | 72,414 | $292.55K | – | no_change |
Pivotal bioVenture Partners Investment Advisor LLCCIK 0001844645 | 42,581 | $172.03K | -51,992 | ↓ DEC |
T3 Companies, LLCCIK 0002052441 | 38,000 | $153.52K | – | no_change |
Board of Trustees of The Leland Stanford Junior UniversityCIK 0001315828 | 35,977 | $145.35K | – | no_change |
PFIZER INCCIK 0000078003 | 31,305 | $137.12K | – | no_change |
Lynx1 Capital Management LPCIK 0001910456 | 30,800 | $124.43K | +30,800 | NEW |
Nan Fung Group Holdings LtdCIK 0001782539 | 29,250 | $118.17K | -29,097 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 28,791 | $116.33K | +9,988 | ↑ INC |
NANO CAP NEW MILLENNIUM GROWTH FUND L PCIK 0001277890 | 27,500 | $111.10K | +7,000 | ↑ INC |
Shay Capital LLCCIK 0001723643 | 14,905 | $60.22K | -367 | ↓ DEC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 11,657 | $47.09K | -4,985 | ↓ DEC |
CITADEL ADVISORS LLCCIK 0001423053 | 10,109 | $40.84K | +10,109 | NEW |
BlackRock, Inc.CIK 0002012383 | 9,711 | $39.23K | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 7,060 | $28.52K | +7,060 | NEW |
MORGAN STANLEYCIK 0000895421 | 3,189 | $12.88K | +61 | ↑ INC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 3,095 | $12.50K | +3,095 | NEW |
Tower Research Capital LLC (TRC)CIK 0001533421 | 1,093 | $4.42K | +370 | ↑ INC |
UBS Group AGCIK 0001610520 | 787 | $3.18K | +272 | ↑ INC |
JPMORGAN CHASE & COCIK 0000019617 | 42 | $179.00 | – | no_change |
Vanguard Global Advisers, LLCCIK 0001811242 | 24 | $97.00 | +24 | NEW |
SBI Securities Co., Ltd.CIK 0001851815 | 10 | $40.00 | – | no_change |
BARCLAYS PLCCIK 0000312069 | 6 | $24.00 | – | no_change |
| Filer | Δ Shares | Value |
|---|---|---|
Lynx1 Capital Management LPNEW | +30,800 | $124.43K |
RENAISSANCE TECHNOLOGIES LLC↑ INC | +22,200 | $311.99K |
CITADEL ADVISORS LLCNEW | +10,109 | $40.84K |
GEODE CAPITAL MANAGEMENT, LLC↑ INC | +9,988 | $116.33K |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +7,060 | $28.52K |
NANO CAP NEW MILLENNIUM GROWTH FUND L P↑ INC | +7,000 | $111.10K |
VANGUARD FIDUCIARY TRUST CONEW | +3,095 | $12.50K |
Tower Research Capital LLC (TRC)↑ INC | +370 | $4.42K |
UBS Group AG↑ INC | +272 | $3.18K |
MORGAN STANLEY↑ INC | +61 | $12.88K |
| Filer | Δ Shares | Value |
|---|---|---|
Pivotal bioVenture Partners Investment Advisor LLC↓ DEC | -51,992 | $172.03K |
Nan Fung Group Holdings Ltd↓ DEC | -29,097 | $118.17K |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↓ DEC | -4,985 | $47.09K |
Shay Capital LLC↓ DEC | -367 | $60.22K |