First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
L1 Capital Pty LtdCIK 0001817646 | 7,789,000 | $43.23M | +4,977,000 | ↑ INC |
Sio Capital Management, LLCCIK 0001482416 | 5,382,965 | $29.88M | +3,508,324 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 4,889,153 | $27.13M | +2,862,186 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 3,789,132 | $21.03M | +2,550,355 | ↑ INC |
PERCEPTIVE ADVISORS LLCCIK 0001224962 | 3,425,476 | $19.01M | +1,750,000 | ↑ INC |
BVF INC/ILCIK 0001056807 | 3,000,000 | $16.65M | +3,000,000 | NEW |
FMR LLCCIK 0000315066 | 2,901,350 | $16.10M | +2,861,719 | ↑ INC |
Ensign Peak Advisors, IncCIK 0001454984 | 2,087,111 | $11.58M | +686,556 | ↑ INC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 1,841,230 | $10.22M | +1,045,161 | ↑ INC |
Rhenman & Partners Asset Management ABCIK 0001599882 | 1,438,625 | $7.98M | +200,000 | ↑ INC |
UBS Group AGCIK 0001610520 | 1,406,836 | $7.81M | +891,111 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,223,107 | $6.79M | +865,298 | ↑ INC |
Vestal Point Capital, LPCIK 0001974915 | 1,144,780 | $6.35M | +1,144,780 | NEW |
Affinity Asset Advisors, LLCCIK 0001773195 | 912,397 | $5.06M | +425,713 | ↑ INC |
Oasis Management Co Ltd.CIK 0001317904 | 865,565 | $4.80M | +789,611 | ↑ INC |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 857,803 | $4.76M | +857,803 | NEW |
SUVRETTA CAPITAL MANAGEMENT, LLCCIK 0001569064 | 850,000 | $4.72M | +850,000 | NEW |
Alyeska Investment Group, L.P.CIK 0001453072 | 750,000 | $4.16M | +200,000 | ↑ INC |
Velan Capital Investment Management LPCIK 0001848809 | 700,000 | $3.88M | +700,000 | NEW |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 653,330 | $3.63M | +653,330 | NEW |
NORTHERN TRUST CORPCIK 0000073124 | 591,046 | $3.28M | +336,398 | ↑ INC |
Capricorn Fund Managers LtdCIK 0001901361 | 500,525 | $2.78M | +500,525 | NEW |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 476,344 | $2.64M | +476,344 | NEW |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 469,583 | $2.61M | +469,583 | NEW |
LMR Partners LLPCIK 0001578621 | 450,000 | $2.50M | +450,000 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
L1 Capital Pty Ltd↑ INC | +4,977,000 | $43.23M |
Sio Capital Management, LLC↑ INC | +3,508,324 | $29.88M |
BVF INC/ILNEW | +3,000,000 | $16.65M |
BlackRock, Inc.↑ INC | +2,862,186 | $27.13M |
FMR LLC↑ INC | +2,861,719 | $16.10M |
ADAR1 Capital Management, LLC↑ INC | +2,550,355 | $21.03M |
PERCEPTIVE ADVISORS LLC↑ INC | +1,750,000 | $19.01M |
Vestal Point Capital, LPNEW | +1,144,780 | $6.35M |
GEODE CAPITAL MANAGEMENT, LLC↑ INC | +1,045,161 | $10.22M |
UBS Group AG↑ INC | +891,111 | $7.81M |
| Filer | Δ Shares | Value |
|---|---|---|
JPMORGAN CHASE & CO↓ DEC | -1,373,353 | $165.63K |
One68 Global Capital, LLC↓ DEC | -268,743 | $220.78K |
CITADEL ADVISORS LLC↓ DEC | -179,099 | $159.96K |
CITIGROUP INC↓ DEC | -173,920 | $40.95K |
Eversept Partners, LP↓ DEC | -98,813 | $2.23M |
Marex Group Ltd↓ DEC | -74,095 | $526.88K |
BARCLAYS PLC↓ DEC | -38,206 | $610.07K |
ROYAL BANK OF CANADA↓ DEC | -1,006 | $11.00K |
PNC FINANCIAL SERVICES GROUP, INC.↓ DEC | -14 | $83.00 |