| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 1, 2026 | Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10% Owner | C | 211,013 | $0.0000 | $0.00 |
| May 1, 2026 | Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10% Owner | C | 1,064,473 | $0.0000 | $0.00 |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 489,486 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 354,824 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 489,486 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 1,419,298 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | P | 277,777 | $18.0000 | $5.00M |
| May 1, 2026 | Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10% Owner | C | 1,275,486 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 489,486 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 354,824 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | P | 277,778 | $18.0000 | $5.00M |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 489,486 | – | – |
| May 1, 2026 | SR ONE CAPITAL MANAGEMENT, LLC | 10% Owner | C | 1,419,298 | – | – |
| May 1, 2026 | Carroll Jill | Director | C | 489,486 | – | – |
| May 1, 2026 | Carroll Jill | Director | C | 1,419,298 | – | – |
| May 1, 2026 | Carroll Jill | Director | P | 277,778 | $18.0000 | $5.00M |
| May 1, 2026 | Carroll Jill | Director | C | 489,486 | – | – |
| May 1, 2026 | Carroll Jill | Director | C | 1,419,298 | – | – |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 652,649 | $0.0000 | $0.00 |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 290,390 | $0.0000 | $0.00 |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 1,345,997 | $0.0000 | $0.00 |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 103,232 | $0.0000 | $0.00 |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 935,466 | $0.0000 | $0.00 |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | P | 555,555 | $18.0000 | $10.00M |
| May 1, 2026 | Novo Holdings A/S | 10% Owner | C | 3,327,734 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 377,948 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 225,843 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 872,868 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 80,291 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 727,585 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 377,948 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 225,843 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 872,868 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 80,291 | – | – |
| May 1, 2026 | FMR LLC | 10% Owner, Other | C | 727,585 | – | – |
| Apr 30, 2026 | Lavelle Erin | Director | A | 26,978 | $0.0000 | $0.00 |
| Apr 30, 2026 | Carlson Douglas R | Chief Financial Officer | A | 211,975 | $0.0000 | $0.00 |
| Apr 29, 2026 | Baranowski Lyn | Chief Executive Officer | A | 501,033 | $0.0000 | $0.00 |
| Apr 29, 2026 | Lazarus Howard | Chief Medical Officer | A | 211,975 | $0.0000 | $0.00 |
| Apr 29, 2026 | Haviland Kate | Director | A | 26,978 | $0.0000 | $0.00 |
| Apr 29, 2026 | Turner Heather D | Director | A | 26,978 | $0.0000 | $0.00 |
| Apr 29, 2026 | Rhodes Melissa | Chief Operating Officer | A | 211,975 | $0.0000 | $0.00 |
| Apr 29, 2026 | Congleton Jon | Director | A | 26,978 | $0.0000 | $0.00 |
| Apr 29, 2026 | Golden Adam H. | General Counsel | A | 254,891 | $0.0000 | $0.00 |