| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 7, 2026 | Bender Jeremy | Director | A | 60,000 | $0.0000 | $0.00 |
| Jul 7, 2026 | Bender Jeremy | Director | A | 30,000 | $0.0000 | $0.00 |
| Jul 1, 2026 | Kilroy Conor | See Remarks | A | 14,858 | $0.0000 | $0.00 |
| Jun 16, 2026 | Gibney Anthony S | See Remarks | S | 12,824 | $6.4200 | $82.33K |
| Jun 11, 2026 | Mattessich Antony C. | Director | A | 30,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Mattessich Antony C. | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Johnson David Michael | Director | A | 30,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Johnson David Michael | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Srivastava Sapna | Director | A | 30,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Srivastava Sapna | Director | A | 15,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Bitetti Teresa Marie | Director | A | 30,000 | $0.0000 | $0.00 |
| Jun 11, 2026 | Bitetti Teresa Marie | Director | A | 15,000 | $0.0000 | $0.00 |
| May 19, 2026 | Holles Natalie C. | See Remarks | A | 2,169,103 | $0.0000 | $0.00 |
| May 19, 2026 | Holles Natalie C. | See Remarks | A | 553,844 | $0.0000 | $0.00 |
| May 19, 2026 | Holles Natalie C. | See Remarks | A | 600,118 | $0.0000 | $0.00 |
| May 7, 2026 | Matrix Capital Management Company, LP | 10% Owner | S | 6,922,870 | $5.6400 | $39.04M |
| Apr 16, 2026 | Kilroy Conor | See Remarks | S | 11,738 | $7.0200 | $82.40K |
| Mar 2, 2026 | Elazzouzi Amy | Senior Vice President, Finance | A | 80,472 | $0.0000 | $0.00 |
| Mar 2, 2026 | Elazzouzi Amy | Senior Vice President, Finance | A | 44,528 | $0.0000 | $0.00 |
| Mar 2, 2026 | Hopkins Janet Jill | Chief Medical Officer | A | 160,944 | $0.0000 | $0.00 |
| Mar 2, 2026 | Hopkins Janet Jill | Chief Medical Officer | A | 89,056 | $0.0000 | $0.00 |
| Mar 2, 2026 | Plavsic Mark | Chief Technology Officer | A | 112,661 | $0.0000 | $0.00 |
| Mar 2, 2026 | Plavsic Mark | Chief Technology Officer | A | 62,339 | $0.0000 | $0.00 |
| Mar 2, 2026 | de los Pinos Elisabet | See Remarks | A | 249,000 | $0.0000 | $0.00 |
| Mar 2, 2026 | de los Pinos Elisabet | See Remarks | A | 166,000 | $0.0000 | $0.00 |
| Mar 2, 2026 | Gibney Anthony S | See Remarks | A | 128,755 | $0.0000 | $0.00 |
| Mar 2, 2026 | Gibney Anthony S | See Remarks | A | 71,245 | $0.0000 | $0.00 |
| Mar 2, 2026 | Kilroy Conor | See Remarks | A | 112,661 | $0.0000 | $0.00 |
| Mar 2, 2026 | Kilroy Conor | See Remarks | A | 62,339 | $0.0000 | $0.00 |
| Feb 17, 2026 | Hopkins Janet Jill | Chief Medical Officer | S | 20,401 | $5.0600 | $103.23K |
| Feb 17, 2026 | de los Pinos Elisabet | See Remarks | S | 47,648 | $5.0600 | $241.10K |
| Feb 17, 2026 | Elazzouzi Amy | Senior Vice President, Finance | S | 8,549 | $5.0600 | $43.26K |
| Feb 17, 2026 | Plavsic Mark | Chief Technology Officer | S | 15,890 | $5.0500 | $80.24K |
| Feb 17, 2026 | Kilroy Conor | See Remarks | S | 12,079 | $5.0500 | $61.00K |
| Jan 20, 2026 | de los Pinos Elisabet | See Remarks | S | 16,928 | $4.8600 | $82.27K |
| Jan 20, 2026 | Elazzouzi Amy | Senior Vice President, Finance | S | 1,581 | $4.8600 | $7.68K |
| Nov 17, 2025 | Hopkins Janet Jill | Chief Medical Officer | S | 17,109 | $5.4200 | $92.73K |
| Oct 29, 2025 | de los Pinos Elisabet | See Remarks | S | 9,049 | $6.3500 | $57.46K |
| Oct 29, 2025 | Elazzouzi Amy | Senior Vice President, Finance | S | 896 | $6.3500 | $5.69K |
| Oct 16, 2025 | Plavsic Mark | Chief Technology Officer | S | 12,169 | $6.3500 | $77.27K |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 2,319 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 1,094 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 4,744 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 547 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 547 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 1,094 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 2,554 | $0.0000 | $0.00 |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | S | 7,722 | $6.7000 | $51.74K |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 2,319 | $4.2500 | $9.86K |
| Aug 18, 2025 | Elazzouzi Amy | Senior Vice President, Finance | M | 1,094 | $3.1600 | $3.46K |