First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
Vivo Capital, LLCCIK 0001674712 | 3,153,640 | $10.79M | +3,153,640 | NEW |
Commodore Capital LPCIK 0001831942 | 2,333,713 | $7.98M | +2,333,713 | NEW |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 2,222,502 | $7.60M | +2,126,819 | ↑ INC |
Spruce Street Capital LPCIK 0002050194 | 1,661,073 | $5.58M | +1,661,073 | NEW |
Almitas Capital LLCCIK 0001596468 | 1,479,129 | $5.06M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 1,011,078 | $3.46M | +1,011,078 | NEW |
Woodline Partners LPCIK 0001784547 | 993,671 | $3.40M | +847,700 | ↑ INC |
Boxer Capital Management, LLCCIK 0002018299 | 749,035 | $2.56M | +749,035 | NEW |
Stonepine Capital Management, LLCCIK 0001440771 | 713,845 | $2.44M | +86,177 | ↑ INC |
AMERIPRISE FINANCIAL INCCIK 0000820027 | 696,181 | $2.38M | +696,181 | NEW |
Sio Capital Management, LLCCIK 0001482416 | 657,200 | $2.25M | +657,200 | NEW |
Ally Bridge Group (NY) LLCCIK 0001822947 | 526,315 | $1.80M | +526,315 | NEW |
Prosight Management, LPCIK 0001617201 | 515,754 | $1.76M | +515,754 | NEW |
BANK OF NOVA SCOTIACIK 0000009631 | 459,194 | $1.57M | – | no_change |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 393,702 | $1.35M | +8,390 | ↑ INC |
BlackRock, Inc.CIK 0002012383 | 318,768 | $1.09M | -4,567 | ↓ DEC |
JANE STREET GROUP, LLCCIK 0001595888 | 303,649 | $1.04M | +285,714 | ↑ INC |
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.CIK 0001536186 | 298,166 | $1.02M | -133,594 | ↓ DEC |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 286,547 | $980.84K | +34,672 | ↑ INC |
BANK OF MONTREAL /CAN/CIK 0000927971 | 260,127 | $889.63K | -161,950 | ↓ DEC |
MORGAN STANLEYCIK 0000895421 | 234,187 | $800.92K | +4,417 | ↑ INC |
CANTOR FITZGERALD, L. P.CIK 0001024896 | 200,000 | $684.00K | +200,000 | NEW |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 198,800 | $679.90K | -139,800 | ↓ DEC |
CITADEL ADVISORS LLCCIK 0001423053 | 155,239 | $530.92K | +39,703 | ↑ INC |
VANGUARD FIDUCIARY TRUST COCIK 0000933478 | 137,708 | $470.96K | +137,708 | NEW |
| Filer | Δ Shares | Value |
|---|---|---|
Vivo Capital, LLCNEW | +3,153,640 | $10.79M |
Commodore Capital LPNEW | +2,333,713 | $7.98M |
MILLENNIUM MANAGEMENT LLC↑ INC | +2,126,819 | $7.60M |
Spruce Street Capital LPNEW | +1,661,073 | $5.58M |
VANGUARD CAPITAL MANAGEMENT LLCNEW | +1,011,078 | $3.46M |
Woodline Partners LP↑ INC | +847,700 | $3.40M |
Boxer Capital Management, LLCNEW | +749,035 | $2.56M |
AMERIPRISE FINANCIAL INCNEW | +696,181 | $2.38M |
Sio Capital Management, LLCNEW | +657,200 | $2.25M |
Ally Bridge Group (NY) LLCNEW | +526,315 | $1.80M |
| Filer | Δ Shares | Value |
|---|---|---|
Peapod Lane Capital LLC↓ DEC | -533,542 | $206.90K |
BANK OF MONTREAL /CAN/↓ DEC | -161,950 | $889.63K |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -139,800 | $679.90K |
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.↓ DEC | -133,594 | $1.02M |
MARSHALL WACE, LLP↓ DEC | -78,411 | $60.53K |
BARCLAYS PLC↓ DEC | -27,918 | $1.37K |
Private Advisor Group, LLC↓ DEC | -10,000 | $42.75K |
BlackRock, Inc.↓ DEC | -4,567 | $1.09M |
FEDERATED HERMES, INC.↓ DEC | -3,157 | $28.46K |
Tower Research Capital LLC (TRC)↓ DEC | -1,466 | $1.96K |