First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
TCG Crossover Management, LLCCIK 0001839948 | 10,000,000 | $21.50M | – | no_change |
BlackRock, Inc.CIK 0002012383 | 7,741,245 | $16.64M | +593,479 | ↑ INC |
Foresite Capital Management IV, LLCCIK 0001704132 | 3,887,200 | $8.36M | – | no_change |
VANGUARD CAPITAL MANAGEMENT LLCCIK 0002100119 | 3,678,722 | $7.91M | +3,678,722 | NEW |
Merck & Co., Inc.CIK 0000310158 | 3,545,719 | $7.62M | – | no_change |
683 Capital Management, LLCCIK 0001404574 | 3,200,000 | $6.88M | -150,000 | ↓ DEC |
BALYASNY ASSET MANAGEMENT L.P.CIK 0001218710 | 2,935,253 | $6.31M | -330,322 | ↓ DEC |
VANGUARD PORTFOLIO MANAGEMENT LLCCIK 0002100121 | 2,583,542 | $5.55M | +2,583,542 | NEW |
GEODE CAPITAL MANAGEMENT, LLCCIK 0001214717 | 2,286,218 | $4.92M | +210,998 | ↑ INC |
JACOBS LEVY EQUITY MANAGEMENT, INCCIK 0000884414 | 2,154,361 | $4.63M | -18,841 | ↓ DEC |
Spruce Street Capital LPCIK 0002050194 | 2,101,068 | $4.52M | +983,082 | ↑ INC |
Ikarian Capital, LLCCIK 0001778253 | 2,082,606 | $4.48M | – | no_change |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 1,979,226 | $4.26M | +646,312 | ↑ INC |
STATE STREET CORPCIK 0000093751 | 1,865,526 | $4.01M | +51,228 | ↑ INC |
FMR LLCCIK 0000315066 | 1,796,104 | $3.86M | -435,067 | ↓ DEC |
MEDICI CAPITAL LLCCIK 0001777234 | 1,652,520 | $3.55M | +152,000 | ↑ INC |
Eversept Partners, LPCIK 0001697013 | 1,351,106 | $2.90M | +344,943 | ↑ INC |
Euclidean Capital LLCCIK 0001825034 | 1,307,858 | $2.81M | – | no_change |
RENAISSANCE TECHNOLOGIES LLCCIK 0001037389 | 1,287,691 | $2.77M | -255,959 | ↓ DEC |
TWO SIGMA INVESTMENTS, LPCIK 0001179392 | 1,279,306 | $2.75M | +239,650 | ↑ INC |
DEUTSCHE BANK AG\CIK 0000948046 | 1,092,903 | $2.35M | +57,749 | ↑ INC |
DEERFIELD MANAGEMENT COMPANY, L.P.CIK 0001009258 | 1,055,192 | $2.27M | – | no_change |
ADAR1 Capital Management, LLCCIK 0001940272 | 1,050,000 | $2.26M | -58,000 | ↓ DEC |
DAFNA Capital Management LLCCIK 0001389933 | 908,351 | $1.95M | – | no_change |
Elmind Capital, LPCIK 0002052213 | 900,000 | $1.94M | – | no_change |
| Filer | Δ Shares | Value |
|---|---|---|
VANGUARD CAPITAL MANAGEMENT LLCNEW | +3,678,722 | $7.91M |
VANGUARD PORTFOLIO MANAGEMENT LLCNEW | +2,583,542 | $5.55M |
Spruce Street Capital LP↑ INC | +983,082 | $4.52M |
MILLENNIUM MANAGEMENT LLC↑ INC | +646,312 | $4.26M |
ACADIAN ASSET MANAGEMENT LLC↑ INC | +596,336 | $8.68K |
BlackRock, Inc.↑ INC | +593,479 | $16.64M |
VANGUARD FIDUCIARY TRUST CONEW | +577,939 | $1.24M |
Affinity Asset Advisors, LLCNEW | +500,000 | $1.07M |
Eversept Partners, LP↑ INC | +344,943 | $2.90M |
BANK OF AMERICA CORP /DE/↑ INC | +246,402 | $818.95K |
| Filer | Δ Shares | Value |
|---|---|---|
JANE STREET GROUP, LLC↓ DEC | -575,249 | $927.22K |
MARSHALL WACE, LLP↓ DEC | -546,393 | $1.33M |
FMR LLC↓ DEC | -435,067 | $3.86M |
BARCLAYS PLC↓ DEC | -356,096 | $91.57K |
BALYASNY ASSET MANAGEMENT L.P.↓ DEC | -330,322 | $6.31M |
SUSQUEHANNA INTERNATIONAL GROUP, LLP↓ DEC | -300,983 | $578.99K |
PANAGORA ASSET MANAGEMENT INC↓ DEC | -259,910 | $1.27M |
RENAISSANCE TECHNOLOGIES LLC↓ DEC | -255,959 | $2.77M |
State of Wyoming↓ DEC | -221,447 | $3.54K |
683 Capital Management, LLC↓ DEC | -150,000 | $6.88M |