First-hand SEC EDGAR 13F-HR institutional holdings: the top 25 holders ranked by market value, plus the largest adds and trims this quarter. Quarter 2026-03-31.
| Filer | Shares | Market Value | Δ Shares | Change |
|---|---|---|---|---|
TCG Crossover Management, LLCCIK 0001839948 | 6,481,085 | $721.67M | -630,511 | ↓ DEC |
UBS Group AGCIK 0001610520 | 4,547,406 | $506.35M | +123,500 | ↑ INC |
Darwin Global Management, Ltd.CIK 0001839209 | 3,468,657 | $352.07M | +290,156 | ↑ INC |
MORGAN STANLEYCIK 0000895421 | 1,704,958 | $189.85M | -1,447,036 | ↓ DEC |
Vestal Point Capital, LPCIK 0001974915 | 1,500,000 | $167.03M | -400,000 | ↓ DEC |
Caligan Partners LPCIK 0001727492 | 1,461,924 | $162.79M | +10,000 | ↑ INC |
ADAR1 Capital Management, LLCCIK 0001940272 | 1,438,019 | $160.12M | +120,690 | ↑ INC |
CITADEL ADVISORS LLCCIK 0001423053 | 1,339,038 | $149.10M | +255,491 | ↑ INC |
WESTFIELD CAPITAL MANAGEMENT CO LPCIK 0001177719 | 1,322,938 | $147.31M | +312,972 | ↑ INC |
FMR LLCCIK 0000315066 | 1,286,373 | $143.24M | -79,284 | ↓ DEC |
SUSQUEHANNA INTERNATIONAL GROUP, LLPCIK 0001446194 | 1,284,782 | $143.06M | -203,854 | ↓ DEC |
Helikon Investments LtdCIK 0001839497 | 1,013,324 | $112.83M | +1,013,324 | NEW |
Eversept Partners, LPCIK 0001697013 | 934,423 | $104.05M | +276,589 | ↑ INC |
BAKER BROS. ADVISORS LPCIK 0001263508 | 875,796 | $97.52M | – | no_change |
Paradigm Biocapital Advisors LPCIK 0001855655 | 772,473 | $86.01M | -645,000 | ↓ DEC |
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.CIK 0002011081 | 765,915 | $85.28M | +73,942 | ↑ INC |
Cormorant Asset Management, LPCIK 0001583977 | 760,000 | $84.63M | -590,000 | ↓ DEC |
BANK OF AMERICA CORP /DE/CIK 0000070858 | 735,729 | $81.92M | +213,440 | ↑ INC |
Octagon Capital Advisors LPCIK 0001839435 | 677,000 | $75.38M | -79,000 | ↓ DEC |
Point72 Asset Management, L.P.CIK 0001603466 | 647,236 | $72.07M | -2,261,918 | ↓ DEC |
Ensign Peak Advisors, IncCIK 0001454984 | 631,838 | $70.36M | +113,491 | ↑ INC |
MILLENNIUM MANAGEMENT LLCCIK 0001273087 | 621,092 | $69.16M | -119,968 | ↓ DEC |
Artia Global Partners LPCIK 0001937964 | 600,747 | $66.89M | -9,900 | ↓ DEC |
JPMORGAN CHASE & COCIK 0000019617 | 635,066 | $64.46M | +179,143 | ↑ INC |
BOOTHBAY FUND MANAGEMENT, LLCCIK 0001549230 | 559,261 | $62.27M | +16,080 | ↑ INC |
| Filer | Δ Shares | Value |
|---|---|---|
Helikon Investments LtdNEW | +1,013,324 | $112.83M |
WESTFIELD CAPITAL MANAGEMENT CO LP↑ INC | +312,972 | $147.31M |
Darwin Global Management, Ltd.↑ INC | +290,156 | $352.07M |
Eversept Partners, LP↑ INC | +276,589 | $104.05M |
CITADEL ADVISORS LLC↑ INC | +255,491 | $149.10M |
BANK OF AMERICA CORP /DE/↑ INC | +213,440 | $81.92M |
DIADEMA PARTNERS LP↑ INC | +200,300 | $30.49M |
Centiva Capital, LPNEW | +179,450 | $19.98M |
JPMORGAN CHASE & CO↑ INC | +179,143 | $64.46M |
Kite Lake Capital Management (UK) LLPNEW | +129,700 | $14.44M |
| Filer | Δ Shares | Value |
|---|---|---|
Point72 Asset Management, L.P.↓ DEC | -2,261,918 | $72.07M |
MORGAN STANLEY↓ DEC | -1,447,036 | $189.85M |
BARCLAYS PLC↓ DEC | -1,218,014 | $10.11M |
JANE STREET GROUP, LLC↓ DEC | -653,616 | $24.00M |
Paradigm Biocapital Advisors LP↓ DEC | -645,000 | $86.01M |
TCG Crossover Management, LLC↓ DEC | -630,511 | $721.67M |
Cormorant Asset Management, LP↓ DEC | -590,000 | $84.63M |
Jefferies Financial Group Inc.↓ DEC | -447,172 | $1.13M |
Vestal Point Capital, LP↓ DEC | -400,000 | $167.03M |
FARALLON CAPITAL MANAGEMENT, L.L.C.↓ DEC | -385,000 | $222.70K |