| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Feb 9, 2026 | Lee Tien-Li | Chief Executive Officer | A | 203,851 | $0.0000 | $0.00 |
| Feb 9, 2026 | Jaiman Manasi | Chief Medical Officer | A | 70,549 | $0.0000 | $0.00 |
| Feb 9, 2026 | Sun Nelson | Chief Financial Officer | A | 70,549 | $0.0000 | $0.00 |
| Dec 11, 2025 | Sun Nelson | Chief Financial Officer | P | 3,000 | $14.4000 | $43.20K |
| Dec 11, 2025 | Lee Tien-Li | Chief Executive Officer | P | 7,000 | $14.4850 | $101.39K |
| Oct 15, 2025 | Jones Bryan | Chief Operating Officer | M | 1,250 | $0.0000 | $0.00 |
| Oct 15, 2025 | Jones Bryan | Chief Operating Officer | M | 1,250 | $4.2400 | $5.30K |
| Oct 15, 2025 | Lee Tien-Li | Chief Executive Officer | M | 1,229 | $0.0000 | $0.00 |
| Oct 15, 2025 | Lee Tien-Li | Chief Executive Officer | M | 1,229 | $4.2400 | $5.21K |
| Sep 15, 2025 | Lee Tien-Li | Chief Executive Officer | P | 3,500 | $9.9442 | $34.80K |
| Sep 15, 2025 | Lee Tien-Li | Chief Executive Officer | P | 6,500 | $9.5106 | $61.82K |
| Sep 12, 2025 | Lee Tien-Li | Chief Executive Officer | P | 5,000 | $8.5031 | $42.52K |
| Sep 11, 2025 | Lee Tien-Li | Chief Executive Officer | P | 6,000 | $7.8210 | $46.93K |
| Sep 10, 2025 | Lee Tien-Li | Chief Executive Officer | P | 9,000 | $7.9125 | $71.21K |
| Sep 9, 2025 | Sun Nelson | Chief Financial Officer | P | 6,000 | $8.0733 | $48.44K |
| Aug 28, 2025 | Lee Tien-Li | Chief Executive Officer | M | 17,209 | $0.0000 | $0.00 |
| Aug 28, 2025 | Lee Tien-Li | Chief Executive Officer | M | 17,209 | $4.2400 | $72.97K |
| Jun 11, 2025 | Graf Susan E | Director | A | 30,508 | $0.0000 | $0.00 |
| Jun 11, 2025 | Jones Bryan | Chief Operating Officer | A | 122,033 | $0.0000 | $0.00 |
| Jun 11, 2025 | Sun Nelson | Chief Financial Officer | A | 209,826 | $0.0000 | $0.00 |
| Jun 11, 2025 | Tong Victor Edward Jr | Director | A | 61,017 | $0.0000 | $0.00 |
| Jun 11, 2025 | Baynes Roy D. | Director | A | 30,508 | $0.0000 | $0.00 |
| Jun 11, 2025 | Jaiman Manasi | Chief Medical Officer | A | 126,999 | $0.0000 | $0.00 |
| Jun 11, 2025 | Chi Jeffrey | Director | A | 61,017 | $0.0000 | $0.00 |
| Jun 11, 2025 | Lee Tien-Li | Chief Executive Officer | A | 549,534 | $0.0000 | $0.00 |
| Feb 14, 2025 | Cormorant Asset Management, LP | Other | C | 800,189 | – | – |
| Feb 14, 2025 | Cormorant Asset Management, LP | Other | P | 187,500 | $16.0000 | $3.00M |
| Feb 14, 2025 | Cormorant Asset Management, LP | Other | C | 800,189 | – | – |
| Feb 14, 2025 | Vickers Venture Fund VI Pte Ltd | 10% Owner | C | 413,491 | $0.0000 | $0.00 |
| Feb 14, 2025 | Vickers Venture Fund VI Pte Ltd | 10% Owner | C | 1,637,411 | $0.0000 | $0.00 |
| Feb 14, 2025 | Vickers Venture Fund VI Pte Ltd | 10% Owner | C | 413,491 | – | – |
| Feb 14, 2025 | Vickers Venture Fund VI Pte Ltd | 10% Owner | C | 1,637,411 | – | – |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | C | 333,412 | $0.0000 | $0.00 |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | C | 2,333,887 | $0.0000 | $0.00 |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | P | 625,000 | $16.0000 | $10.00M |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | P | 625,000 | $16.0000 | $10.00M |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | C | 333,412 | – | – |
| Feb 14, 2025 | Decheng Capital Global Life Sciences Fund IV, L.P. | 10% Owner | C | 2,333,887 | – | – |
| Feb 14, 2025 | Sun Nelson | Chief Financial Officer | C | 59,332 | $0.0000 | $0.00 |
| Feb 14, 2025 | Sun Nelson | Chief Financial Officer | P | 10,000 | $16.0000 | $160.00K |
| Feb 14, 2025 | Sun Nelson | Chief Financial Officer | C | 7,001 | – | – |
| Feb 14, 2025 | Lee Tien-Li | Chief Executive Officer | C | 350,002 | $0.0000 | $0.00 |
| Feb 14, 2025 | Lee Tien-Li | Chief Executive Officer | P | 16,542 | $16.0000 | $264.67K |
| Feb 14, 2025 | Lee Tien-Li | Chief Executive Officer | C | 41,303 | – | – |
| Feb 14, 2025 | Chi Jeffrey | Director | C | 1,130,135 | $0.0000 | $0.00 |
| Feb 14, 2025 | Chi Jeffrey | Director | C | 133,364 | – | – |